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PH 122 > Introduction to Infectious Diseases > Flashcards

Introduction to Infectious Diseases Flashcards

1
Q

He proved that DNA is the material responsible for transmission of genetic traits

A

Oswald Avery

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2
Q

Usual causative organism for secondary infection of burns

A

Pseudomonas

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3
Q

Invasiveness causes further growth at original sites only. True or False?

A

False. Distant sites also

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4
Q 
Distance  microbes   travel   into   the   RT   is \_\_\_ to their size
A. inversely proportional
B. directly proportional
C. not related 
D. none of the above
A

A

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5
Q

Smaller bacteria that enter the respi tract are inhaled directly into the ___

A

alveolar lining

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6
Q

What happens to large microbes (greater than 5 micrometers) in the respiratory tract?

A

They are trapped and swallowed. They do not cause disease anymore.

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7
Q

Females are more prone (10x more than males) to UTI. Why?

A

shorter urethra

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8
Q

4 ways microbes can utilise to enter the body. enumerate

A

Ingestion
Sexual transmission
Insect/animal bites
Injection

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9
Q

Prions are composed of abnormal forms of host protein, Prion Proteins (PrP), that are normally found in ___

A

neurons

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10
Q

What are Transmissible Spongiform Encelopathies?

A

Prions undergo conformational changesthat confers resistance to proteases

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11
Q

another name for the clinical manifestation of human cannibalism (prion-caused)

A

kuru

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12
Q

Bovine spongiform encephalopathy is also known as __

A

mad cow’s disease

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13
Q

Composed of nucleic acid genome surrounded by capsidand sometimes encased in lipid membrane

A

virus

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14
Q

Prions undergo conformational changes and aggregated deposit in neurons. These deposits are called __

A

intracellular and cytoplasmic inclusions

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15
Q 
Which is not a respiratory virus?
A.Adenovirus
B.Rhinovirus
C.Influenza virus
D.Rotavirus
A

D

Rotavirus - childhood diarrhea

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16
Q 
Which is not a digestive system virus?
A.Mumps virus
B.Rotavirus
C.Cytomegalovirus
D.Hepatitis A-E virus
A

C

Cytomegalovirus causes a systemic disease w/ hematopoeitic disorders.

17
Q

What do measles, herpes zoster and varicella have in common.

A

They are all systemic viruses with eruptions.

18
Q

Cytomegalovirus causes a systemic disease w/hematopoeitic disorders. Name two other ones that do this too.

A

HIV

Epstein-Barr virus

19
Q

Papillomaviruses, Polioviruses and JC Viruses have what in common?

A

warty growths

20
Q

virus associated with infectious mononucleosis

A

Epstein-Barr virus

21
Q

Brucella melitensis causes brucellosis, or __

A

undulant fever

22
Q

content of fungi cell wall

A

chitin

23
Q

content of fungi cell membrane

A

ergosterol

24
Q

enumerate two growth patterns of fungi

A

yeast and hyphae

25
Q

Some fungi exhibit thermal dimorphism. Which is false?
A)At room temperature they are seen as hyphae
B)At body temperature they are formed as yeast
C)They are seen as hyphae or yeast depending on the environment they are in
D)A and B

A

C

26
Q

sexual spores are called __

A

ascospores

27
Q

asexual spores are called __

A

conidia

28
Q

causative agent of athlete’s foot

A

Tinea pedia

29
Q

Sporotrichosis is __ mycosis
A. superficial
B. subcutaneous
C. deep

A

B

30
Q

smallest free-living bacteria, aerobic, has a special characteristic of metabolising glucose, lack cell wall

identify

A

Mycoplasma

31
Q

small bacteria that can only grow inside cells like viruses;arthropods serve as vectors

identify

A

Rickettsia

32
Q

motile, single-celled eukaryotes are also called __

A

protozoa

33
Q

False about malaria
A. one of the most significat protozoans in our country
B. transmitted by female Aedes aegypti mosquito
C. has erythrocytic (infect RBC) and exo-erythrocytic (in the liver) stages

A

B

Anopheles dapat

34
Q

identify

infecting macrophages; from blood-sucking insects

A

Leishmania

35
Q

identify

sexually tranmitted; causes trichomoniasis; usually found in papsmear

A

Trichomonas vaginalis

36
Q

Three mechanisms by which a microbe causes disease

A
  1. Enter host cells and directly cause cell death
  2. Release endotoxins or exotoxins
  3. Induce host immune and inflammatory response to the micro
37
Q
  • predilection to infect certain cell types
  • determined by host cell receptors for a particular virus

identify

A

tropism

38
Q

What retrovirus protein binds to CD4+ T cells?

A

HIV gp120 protein

39
Q

Rhinoviruses bind to ___found in nasal mucosa

A

intercellular adhesion molecule-1

PH 122 (17 decks)

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