intro to upper GI tract W4 Flashcards
GI tract walls layers?
mucosa
submucosa
muscularis
serosa
mucosa features?
lining of GI tract containing 3 layers including a thin layer of muscle
submucosa features?
connective tissue where blood vessels and nerves lie
musuclaris features
layers of smooth muscle and enteric nervous system
serosa features
part of visceral layer of peritoneum
typical length of the oesophagus?
25cm
3 sections of the oesophagus?
cervical
thoracic
abdominal
what is the oesophagus lined with and why
stratified squamous epithelium
thick and robust, food items wont tear it.
last 1cm is columnar epithelium (pinker than squamous)
types of cancer in the oesophagus arising from the epithelium?
squamous carcinoma - from squamous epithelium
adenocarcinoma - from columnar epithelium
types of muscle control in the oesophagus?
upper 3rd = voluntary (striated)
lower 3rd = involuntary (smooth)
middle = mixed
sphincters of the oesophagus?
upper oesophageal sphincter
lower oesophageal sphincter
features of upper oesophageal sphincter?
muscular
primary cricopharyngeus
stops air getting into gut
features of lower oesophageal sphincter?
comprises a thickened muscular layer in the lower oesophagus and cardia of the stomach (intrinsic) and the diaphragm (extrinsic)
prevents acid/food reflux
types of hiatus hernia
sliding - stomach slips into thoracic cavity (no abdominal oesophagus)
paraesophageal - stomach slips through diaphragm parallel to oesophagus (rarer)
main symptom of hiatus hernia?
acid/food reflux
4 sections of the stomach?
cardia
fundus
body
antrum
name for sphincter from stomach to duodenum
pylorus (pyloric sphincter)
what is the mucosa in the stomach folded into? what is found between these?
rugae (folds)
gastric pits found between these.
features of stomach muscles?
lie in oblique layers - strong and effective
features of the gastric mucosa?
glands
chief cells
parietal cells
endocrine cells
gastric mucosa - glands function?
secrete mucous which protects the mucosa from the acid environment from the stomach
gastric mucosa - chief cells function?
secrete enzymes of gastric juice (pepsin)
gastric mucosa - parietal cells function?
secrete hydrochloric acid and intrinsic factor (imp for b12 absorption)
gastric mucosa - endocrine cells function?
secrete ghrelin (hormone which promotes appetite) and gastrin (digestive hormone)