functional upper GI disorders W7

Question 1

differential diagnosis for functional GI disorders?

Answer 1

no gastroesophageal reflux
no gastrointestinal malignancy
no alarm symptoms and under 55y
HP -ve
normal endoscopy
exclude systemic or metabolic disease (eg diabetes)

Question 2

4 types of functional upper GI disorders?

Answer 2

functional dyspepsia
belching disorders
chronic nausea and vomiting disorders
rumination syndrome

Question 3

functional dyspepsia diagnostic criteria?

Answer 3

one or more of the following:
-bothersome postprandial fullness
-bothersome early satiety
-bothersome epigastric pain
AND
no evidence of structural disease that is likely to explain the symptoms.

Question 4

what is dyspepsia?

Answer 4

indigestion

Question 5

subclassifications of functional dyspepsia?

Answer 5

post prandial distress syndrome (PDS)
epigastric pain syndrome (EPS)

Question 6

PDS features?

Answer 6

fullness and satiety but no pain
gastric dysmotility or abnormal accommodation

Question 7

EPS features?

Answer 7

pain and burning - visceral hypersensitivity

Question 8

pathophysiology of functional dyspepsia?

Answer 8

gastroduodenal motor and sensory dysfunction, as well as impaired mucosal integrity, low grade immune activation, and dysregulation of the gut-brain axis

can be triggered by acute infection

associated with anxiety and depression

Question 9

treatment?

Answer 9

SSRIs (antidepressants)
PPIs