GI emergencies W8 Flashcards
acute UGI bleed - main causes?
peptic ulcer disease
varices
variceal bleed incidence/prognosis?
occurs in 30-35% of cirrhotic patients
1/3 episodes are fatal
1/3 survivals will rebleed within 6 months
1/3 will survive >1y
variceal bleeds and transfusion?
restrictive transfusion important to avoid rapid expansion of volume, which may lead to further bleed.
variceal bleed management?
endoscopy early on (6-12h)
oesophageal = banding
gastric/ectopic = histoacryl or thrombin (larger veins will leave a hole if banding)
IV antibiotics, iv terlipressin (reduce portal pressure)
peptic ulcer disease (PUD)?
ulcer in oesophagus, stomach, duodenum due to acid
how is an ulcer different to an erosion?
penetrates muscularis mucosae. can be acute or chronic
peptic ulcer causes?
H. Pylori (>90% DUs, >70% GU’s)
NSAIDs (deplete mucosal defence)
perforated ulcer presentation? mortality, treatment?
sudden severe abdominal pain spreading to shoulder tip.
peritonitis, shock
air under diaphragm (bilateral)
mortality 10%
emergency surgery
bleeding ulcer presentation? morality?
haematemesis (vomiting blood)
melaena (black stool)
mortality 10%
management of UGIB? (upper GI bleeding)
assess need for blood transfusion
timely endoscopy
rescue therapies?
angiography/embolism
when endoscopy fails -> failed primary haemostasis
patient unfit for laparotomy
site would render surgery extensive
HP eradication/NSAIDs
important not to forget to look for HP
eradicate, check complete 6-12 weeks later with stool antigen test.
stop NSAIDs
surgical intervention?
<5% of patients need surgery
usually if all else fails
worse prognosis for deep ulcers in posterior duodenum (erosion of gastroduodenal artery)
acute pancreatitis commonest causes?
gallstones
alcohol
presentation of acute pancreatitis?
acute epigastric pain
colicy or continuous pain
nauesa, vomiting
collapse or hypotension
fever, tachycardia
obstructive jaundice