Intracellular Bacteria Flashcards
What bacteria are obligate intracellular organisms?
Chlamydia
Coxiella
Rickettsia
What bacteria are facultative intracellular pathogens?
Listeria Mycobacterium Neisseria Salmonella Yersinia pestis Leginoella Brucella Francisella
Low is Listeria acquired?
Unpasteurized dairy products
Cold deli meats
Transplacental transmission
Vaginal transmission during birth
What diseases can Listeria cause in pregnant women?
Amnionitis
Sepsis
Spontaneous abortion
What diseases can Listeria cause in the newborn?
Granulomatosis infantiseptica
Neonatal meningitis
What diseases can Listeria cause in health individuals and immunocompromised individuals?
Healthy- gastroenteritis
Immunocompromised- meningitis
What is the only intracellular pathogen to reside within a phagolysosome?
Coxiella
Where in the cell does Listeria reside?
Cytosol- lyses the phagocytic vacuole
What class of antibiotics can target intracellular pathogens?
Tetracyclines