Interdisciplinary Medicine Flashcards
Submandibular swelling and edema of the mouth floor, drooling, neck pain, dysphagia, or dysphonia
Ludwig angina
MKSAP 20
Ludwig angina is a serious, potentially life-threatening cellulitis of the submandibular space.
First test for premenopausal AUB
Pregnancy test
MKSAP 20
AUB stands for abnormal uterine bleeding.
Most effective smoking cessation pharmacotherapy
Varenicline with nicotine replacement therapy
MKSAP 20
Varenicline is a non-nicotine medication that helps reduce cravings.
Test result that should prompt evaluation for hereditary or clonal mast cell diseases
Tryptase level >8 ng/mL
MKSAP 20
Elevated tryptase levels can indicate mast cell activation disorders.
Pharmacologic treatment of bacterial conjunctivitis
Topical trimethoprim-polymyxin B or erythromycin
MKSAP 20
These are commonly prescribed antibiotics for treating bacterial conjunctivitis.
Difficulty managing oral secretions, severe odynophagia/dysphagia, tachypnea, and stridor
Epiglottitis
MKSAP 20
Epiglottitis is an inflammation of the epiglottis that can obstruct the airway.
USPSTF recommendation for peripartum depression prevention in at-risk patients
CBT or interpersonal therapy
MKSAP 20
CBT stands for cognitive behavioral therapy.
Purpose of cerumen
Protect, clean, and lubricate the external auditory canal
MKSAP 20
Cerumen is commonly known as earwax.
First-line therapy when antibiotic treatment is indicated for acute rhinosinusitis
Amoxicillin-clavulanate or amoxicillin
MKSAP 20
These antibiotics are effective for treating acute bacterial rhinosinusitis.
Most common cause of tinnitus
Hearing loss
MKSAP 20
Tinnitus is often associated with age-related hearing loss.
First-line treatment for premature ejaculation
Daily SSRI, on-demand clomipramine, or topical penile anesthetic
MKSAP 20
SSRIs are often used off-label for treating premature ejaculation.
Oral antibiotic treatment of acute bacterial prostatitis
Trimethoprim-sulfamethoxazole, ciprofloxacin, or levofloxacin
MKSAP 20
These antibiotics are commonly used to treat bacterial prostatitis.
Early-adult onset of delusions, hallucinations, disorganized or catatonic behavior
Schizophrenia
MKSAP 20
Schizophrenia typically manifests in late adolescence to early adulthood.
Criteria for diagnosis of any female sexual disorder
Persistent symptoms and distress >75% of time for ≥6 months
MKSAP 20
This criterion helps in diagnosing various female sexual dysfunctions.
Acute painful vision loss, afferent pupillary defect, central scotoma
Optic neuritis
MKSAP 20
Optic neuritis is often associated with multiple sclerosis.
Evaluation of recurrent unilateral epistaxis
Nasal endoscopy
MKSAP 20
This procedure helps visualize the nasal cavity and identify bleeding sources.
Testicular pain and absent cremasteric reflex
Testicular torsion
MKSAP 20
Testicular torsion is a surgical emergency that requires immediate intervention.
Fever, rash (including urticaria), headache, and polyarthritis 1-2 weeks after starting rituximab
Serum sickness
MKSAP 20
Serum sickness is an immune complex-mediated condition that can occur after certain medications.
Early complement deficiency infection risk
Encapsulated organisms
MKSAP 20
Patients with complement deficiencies are at increased risk for infections by encapsulated bacteria.
Antidepressants capable of causing the serotonin syndrome
SSRIs, SNRIs, bupropion, MAO inhibitors
MKSAP 20
Serotonin syndrome can occur with excessive serotonergic activity.
Duration of postpartum period
Begins after birth and extends up to 1 year thereafter
MKSAP 20
The postpartum period is crucial for maternal recovery and bonding.
Approach to sudden-onset hearing loss (within 72 hours)
Urgent audiology referral, MRI, consideration of glucocorticoids
MKSAP 20
Early intervention can be critical for recovery of hearing.
Food allergy often occurring 2-6 hours after ingesting mammalian meat
α-Gal syndrome
MKSAP 20
α-Gal syndrome is associated with tick bites and leads to delayed allergic reactions.
Microbial origin for acute bacterial sialadenitis
Commonly polymicrobial, often with Staphylococcus aureus and anaerobes
MKSAP 20
This condition involves inflammation of the salivary glands.
Nonhormonal drugs for vasomotor symptoms of menopause
SSRIs, SNRIs, gabapentin, fezolinetant
MKSAP 20
These options provide alternatives for women who cannot use hormone therapy.
Sudden, painless, severe monocular vision loss
Central retinal artery occlusion
MKSAP 20
Most common cause of vaginitis
Bacterial vaginosis
MKSAP 20
Management of somatic symptom disorder
Acknowledgment of symptoms, therapeutic relationship, CBT
MKSAP 20
Most effective nicotine replacement strategy
Combination of short- and long-acting forms
MKSAP 20
Most common cause of acute urinary retention in men
BPH
MKSAP 20
Treatment of anovulatory AUB when fertility is desired
Medroxyprogesterone acetate
MKSAP 20
Acute eye pain, halos around lights, nausea/vomiting
Acute angle-closure glaucoma
MKSAP 20
Laboratory test indicated in patients with recurrent Neisseria infections
Total hemolytic complement (CH50) level
MKSAP 20
Over-the-counter medication used as adjunctive therapy for opioid use disorder
Intranasal naloxone
MKSAP 20
Premenstrual breast pain resolving with menstrual cycle onset
Cyclic mastalgia
MKSAP 20
Recommended strategy for benzodiazepine treatment of alcohol withdrawal
Symptom-triggered approach (CIWA-Ar)
MKSAP 20
Medications for postcoital contraception
Levonorgestrel (3-day window), ulipristal (5-day window)
MKSAP 20
Immunizations avoided during pregnancy
Live vaccines (e.g. varicella, HPV, MMR, live attenuated influenza, live attenuated zoster)
MKSAP 20
Smoking cessation drug contraindicated in seizure disorder
Bupropion
MKSAP 20
Severe cough paroxysms persisting for >2 weeks, often with posttussive emesis
Pertussis (whooping cough)
MKSAP 20
Hormonal contraception options when estrogen is contraindicated
Progestin-containing injection, implant, or pill; IUD
MKSAP 20
Major withdrawal symptoms within 48 hours of last alcoholic drink
Alcoholic hallucinosis and seizures
MKSAP 20
Vaginitis that requires partner treatment
Trichomoniasis
MKSAP 20
Urine leakage with coughing, sneezing, laughing
Stress urinary incontinence
MKSAP 20
Treatment of asymptomatic vaginal candidiasis
None
MKSAP 20
Contraindication to PDE-5 inhibitors for ED
Nitrate therapy
MKSAP 20
Treatment of anorexia nervosa
Psychotherapy, family therapy, and monitored dietary intake
MKSAP 20
Initial imaging test for breast mass in women <30 years
Ultrasonography
MKSAP 20
Impulsive overeating with compensatory behaviors, normal BMI
Bulimia nervosa
MKSAP 20
Breast imaging test of choice for pregnant women
Ultrasonography
MKSAP 20
Contraindicated vaccines in CVID
Any live vaccine
MKSAP 20
CVID stands for Common Variable Immunodeficiency, a disorder affecting the immune system.
Treatment of genitourinary syndrome of menopause
Moisturizers, lubricants, topical estrogen
MKSAP 20
This syndrome is characterized by symptoms such as vaginal dryness and discomfort.
Clinical diagnosis of bacterial vaginosis requires any three of the following:
- Vaginal pH >4.5
- Thin, homogenous discharge
- Positive whiff test result
- 20% clue cells
MKSAP 20
Bacterial vaginosis is a common vaginal infection caused by an imbalance of bacteria.
First-line treatment of ADHD
Methylphenidate, amphetamine
MKSAP 20
ADHD stands for Attention-Deficit/Hyperactivity Disorder.
Laboratory tests when there is high suspicion for hereditary angioedema
C1 esterase inhibitor and C4 complement levels
MKSAP 20
Hereditary angioedema is a genetic condition that causes severe swelling.
Common sexual adverse effects of SSRIs
- Reduced libido
- Anorgasmia
- Delayed orgasm
MKSAP 20
SSRIs are selective serotonin reuptake inhibitors used primarily as antidepressants.
Tenderness with pushing on the tragus, pulling on the pinna suggests:
Acute otitis externa
MKSAP 20
Also known as swimmer’s ear, this condition is an infection of the outer ear canal.
FDA-approved pharmacologic treatments for female sexual dysfunction include:
- Flibanserin
- Bremelanotide
MKSAP 20
These medications target hypoactive sexual desire disorder in women.
Management of suspicious breast mass with negative imaging findings
Biopsy
MKSAP 20
A biopsy helps determine if the mass is benign or malignant.
Initial evaluation for overflow urinary incontinence involves:
Ultrasonography for postvoid residual urine volume measurement
MKSAP 20
This evaluation helps assess the bladder’s ability to empty completely.
Initial treatment of urge urinary incontinence
Bladder training and timed voiding
MKSAP 20
This approach helps patients regain control over urination.
Preferred diagnostic test for trichomoniasis
Nucleic acid amplification testing
MKSAP 20
Trichomoniasis is a sexually transmitted infection caused by a parasite.
Severe eye pain, photophobia, scleral edema/redness indicates:
Scleritis
MKSAP 20
Scleritis is an inflammation of the sclera, the outer layer of the eye.
Noninfectious disease risk in early complement deficiency includes:
SLE
MKSAP 20
SLE stands for Systemic Lupus Erythematosus, an autoimmune disease.
Initial treatment of primary dysmenorrhea involves:
- NSAIDs
- Contraception (e.g., estrogen-progesterone and progesterone-only methods)
MKSAP 20
Primary dysmenorrhea refers to painful menstrual cramps without an underlying condition.
Earliest symptom of primary open-angle glaucoma
Peripheral visual field loss
MKSAP 20
This condition is a leading cause of blindness, often without symptoms until advanced stages.
Recurrent nausea and vomiting relieved by prolonged hot showers suggests:
Cannabis hyperemesis syndrome
MKSAP 20
This syndrome is associated with chronic cannabis use.
Necessary test for women of reproductive age presenting with acute pelvic pain
Pregnancy test
MKSAP 20
This test is crucial to rule out ectopic pregnancy or other pregnancy-related complications.
Autonomic activation and altered mental status ≥48 hours after last alcoholic drink indicates:
Delirium tremens
MKSAP 20
This condition is a severe form of alcohol withdrawal.
Conditions for which patients with CVID are at increased risk include:
- Autoimmune disease
- Inflammatory bowel disease
- Noncaseating granulomas
- Bronchiectasis
- Malignancy
MKSAP 20
CVID can lead to various complications due to immune system deficiencies.
Vulvar dryness and pale, dry vaginal walls with decreased rugae suggest:
Genitourinary syndrome of menopause (vaginal atrophy)
MKSAP 20
This condition occurs due to decreased estrogen levels during menopause.
Impulsive overeating with compensatory behaviors and low BMI indicates:
Anorexia nervosa, binging subtype
MKSAP 20
This subtype is characterized by episodes of binge eating followed by compensatory actions.
First-line treatment of allergic rhinitis is:
Intranasal glucocorticoid monotherapy
MKSAP 20
Allergic rhinitis is an allergic reaction that causes sneezing, congestion, and other symptoms.
Most common location for endometriosis is:
Ovaries
MKSAP 20
Endometriosis occurs when tissue similar to the lining of the uterus grows outside the uterus.
Management of cyclic mastalgia includes:
- Reassurance
- Appropriate breast support
- Topical NSAID
MKSAP 20
Cyclic mastalgia refers to breast pain that occurs in sync with the menstrual cycle.
Initial drug therapy for LUTS
α-Blocker
MKSAP 20
LUTS stands for lower urinary tract symptoms.
Most effective postcoital contraception
Copper IUD within 5 days of intercourse
MKSAP 20
IUD stands for intrauterine device.
Treatment of functional urinary incontinence
Prompted voiding
MKSAP 20
Functional urinary incontinence is often related to cognitive impairment.
Risk for VTE with progestin-only contraception
None
MKSAP 20
VTE stands for venous thromboembolism.
Recommended treatment for urticaria
Nonsedating, long-acting antihistamines (e.g., fexofenadine)
MKSAP 20
Urticaria is commonly known as hives.
Impulsive overeating and loss of control over eating
Binge eating disorder
MKSAP 20
Binge eating disorder is characterized by recurrent episodes of eating large quantities of food.
Chaotic interpersonal relationships, emotional lability, self-destructive behaviors
Borderline personality disorder
MKSAP 20
This disorder often includes intense episodes of anger, depression, and anxiety.
Most common cause of galactorrhea
Pregnancy
MKSAP 20
Galactorrhea is the inappropriate lactation not associated with childbirth.
“Bag of worms” scrotal mass that becomes smaller with elevation and supine positioning
Varicocele
MKSAP 20
Varicocele is caused by enlarged veins within the scrotum.
Risk of prescribing antidepressant monotherapy in bipolar disorder
Precipitation of a manic episode
MKSAP 20
Antidepressant monotherapy can destabilize mood in bipolar patients.
MKSAP 20
First-line therapy for stress urinary incontinence
Pelvic floor muscle training
MKSAP 20
This training helps strengthen the pelvic muscles.
First-line pharmacotherapy for ED
PDE-5 inhibitors
MKSAP 20
PDE-5 stands for phosphodiesterase type 5.
Symptom that must be present to diagnose major depression
Either depressed mood or anhedonia
MKSAP 20
Anhedonia refers to the loss of interest or pleasure in most activities.
Treatment of generalized anxiety disorder
CBT, SSRIs, SNRIs
MKSAP 20
CBT stands for cognitive-behavioral therapy, SSRIs are selective serotonin reuptake inhibitors, and SNRIs are serotonin-norepinephrine reuptake inhibitors.
Intrusive thoughts/impulses and repetitive behaviors
OCD
MKSAP 20
OCD stands for obsessive-compulsive disorder.
Treatment of rhinitis medicamentosa
Cessation of topical decongestant and addition of intranasal glucocorticoids
MKSAP 20
Rhinitis medicamentosa is a condition caused by overuse of decongestant nasal sprays.
Most effective treatment of bulimia nervosa
CBT
MKSAP 20
Cognitive-behavioral therapy is effective in addressing the underlying issues of bulimia.
Repetitive behaviors and difficulties in social interaction
Autism spectrum disorder
MKSAP 20
Autism spectrum disorder encompasses a range of conditions characterized by challenges with social skills, repetitive behaviors, and communication.
Indicators of complicated otitis media
Fever, posterior ear pain, facial nerve paralysis
MKSAP 20
Complicated otitis media may require surgical intervention.
Treatment for subconjunctival hemorrhage
None; usually resolves spontaneously within several weeks
MKSAP 20
Subconjunctival hemorrhage is often harmless.
Most common cause of sensorineural hearing loss
Presbycusis
MKSAP 20
Presbycusis is age-related hearing loss.
Irritative voiding accompanied by new onset of perineal pain and fever
Acute prostatitis
MKSAP 20
Acute prostatitis is an infection of the prostate gland.
Ultrasound finding that warrants endometrial biopsy in postmenopausal AUB
Endometrial stripe >4 mm
MKSAP 20
AUB stands for abnormal uterine bleeding.
Drusen and neovascularization
Wet AMD
MKSAP 20
AMD stands for age-related macular degeneration.
Treatment of panic disorder
SSRIs/SNRIs, CBT, or both
MKSAP 20
Panic disorder often requires a combination of medication and therapy.
Excessive anxiety for ≥6 months causing functional impairment
Generalized anxiety disorder
MKSAP 20
Generalized anxiety disorder is characterized by chronic anxiety and worry.
Tool for assessing response to therapy in depression
PHQ-9
MKSAP 20
PHQ-9 stands for Patient Health Questionnaire-9.
Testicular pain relieved with scrotal elevation
Epididymitis
MKSAP 20
Epididymitis is an inflammation of the epididymis.
Treatment of corneal abrasion in the setting of contact lens use
Topical antibiotics with antipseudomonal activity
MKSAP 20
This is to prevent infections associated with contact lens wear.
Antibiotics for epididymitis in men at risk for STIs
Ceftriaxone and doxycycline
MKSAP 20
This combination covers common sexually transmitted infections.
Initial imaging test for breast mass in women ≥30 years
Mammography
MKSAP 20
Mammography is the standard screening technique for breast cancer.
Recurrence criteria for long-term depression drug therapy
≥3 episodes of major depressive disorder
MKSAP 20
Recurrence indicates a need for ongoing treatment.
Eye pain, photophobia, decreased vision, ciliary flush
Anterior uveitis (iritis)
MKSAP 20
Anterior uveitis is an inflammation of the uvea.
Intrusive memories of a traumatic event
PTSD
MKSAP 20
PTSD stands for post-traumatic stress disorder.
Indications for antibiotics in acute rhinosinusitis
Symptoms >10 days; severe symptoms/high fever ≥3 days; worsening symptoms after initial improvement
MKSAP 20
Acute rhinosinusitis typically resolves without antibiotics.
Recommended test for all patients first presenting with ED
Morning total testosterone level
MKSAP 20
ED stands for erectile dysfunction.
Number of Centor criteria suggesting testing for bacterial pharyngitis
Three (consider with two)
MKSAP 20
The Centor criteria help determine the likelihood of streptococcal infection.