Foundations of Clinical Practice Flashcards
Indication for recombinant zoster vaccine
Age ≥50 years or 19-49 years and immunodeficient/immunocompromised
MKSAP 20
What is substituted judgment?
Surrogate care decisions based on patient’s previously expressed preferences and values
MKSAP 20
HIV screening frequency for average-risk persons
One-time screening
MKSAP 20
Perioperative management of biologic agents for non-SLE rheumatologic disease
Withhold preoperatively; perform surgery just after the next dose would have been due
MKSAP 20
USPSTF recommendation for primary prevention of preeclampsia in ASCVD risk I patients
Low-dose aspirin
MKSAP 20
Influenza formulation recommended for adults ≥65 years of age
Inactivated (standard or high dose) or recombinant influenza vaccine
MKSAP 20
Recommended minimum weekly physical activity
150-300 minutes of moderate-intensity or 75 minutes of vigorous-intensity aerobic activity
MKSAP 20
Increase in disease probability with positive LRs of 2, 5, and 10
15%, 30%, and 45%
MKSAP 20
What is the responsibility when a colleague is impaired or unable to carry out clinical responsibilities?
Report to appropriate authorities and identify appropriate sources of help
MKSAP 20
Perioperative management of aspirin for secondary prevention
Continue perioperatively for elective noncardiac surgery
MKSAP 20
Indication for annual influenza vaccination
All adults
MKSAP 20
Role of vitamin D supplementation in fall prevention
None
MKSAP 20
Initial agent for radiation-induced vomiting
Serotonin antagonists (ondansetron, granisetron)
MKSAP 20
Recommendation for enteral/parenteral nutritional support at end of life
Avoid
MKSAP 20
Components of patient decision-making capacity
Can understand relevant information and communicate choice consistent with information and stated values
MKSAP 20
Intervention when a medical error is discovered
Error disclosure with compassion and concern for patient
MKSAP 20
What is the bias that occurs automatically and unintentionally?
Implicit bias
MKSAP 20
Number one cause of preventable disease, disability, and death in U.S.
Smoking
MKSAP 20
Study type providing the highest level of evidence
Systematic review
MKSAP 20
CDC-recommended HIV screening frequency for MSM
At least annually
MKSAP 20
Rate of diagnostic error in clinical decision making
10%
MKSAP 20
Age indications for HPV vaccination
11-12 years or between 13 and 26 years
MKSAP 20
USPSTF criterion for DM screening in patients aged 35-70 years
Obesity/overweight
MKSAP 20
Time to delay elective noncardiac surgery after stroke or TIA
At least 6 months
MKSAP 20
Prerequisite for genetic testing
Genetic counseling
MKSAP 20
Patients who should undergo preoperative screening for OSA
All patients
MKSAP 20
OSA stands for Obstructive Sleep Apnea, a condition that can complicate anesthesia and surgery.
Strongest clinical study design
Randomized controlled trial
MKSAP 20
This design minimizes bias and allows for the comparison of different interventions.
Perioperative management of untreated subclinical hypothyroidism
Proceed to surgery without further testing/treatment
MKSAP 20
Subclinical hypothyroidism generally does not require intervention prior to surgery.
Four-step quality improvement method
Plan-Do-Study-Act (PDSA) cycle
MKSAP 20
This method is commonly used for continuous quality improvement in healthcare.
Test’s ability to accurately detect those with the disease
Sensitivity
MKSAP 20
Sensitivity measures the proportion of true positives among those with the disease.
Only indication for routine preoperative spirometry
Planned lung resection
MKSAP 20
Routine spirometry is not indicated for all patients but is necessary for those undergoing lung surgery.
USPSTF screening criterion for intimate partner violence
Women of childbearing age
MKSAP 20
The United States Preventive Services Task Force recommends screening in this demographic due to higher risk.
Contraindication to elective surgery in liver disease
MELD score >20
MKSAP 20
MELD stands for Model for End-Stage Liver Disease, and a score above 20 indicates significant liver dysfunction.
Minimum preoperative DAPT duration after bare metal stent placement
14-30 days
MKSAP 20
DAPT refers to dual antiplatelet therapy, crucial for preventing stent thrombosis.
Postoperative rigidity, fever, confusion, and autonomic instability in patient with Parkinson disease
Parkinsonism-hyperpyrexia syndrome (dopamine agonist withdrawal)
MKSAP 20
This syndrome can occur after abrupt withdrawal of dopaminergic medications.
Typical time to restart DOACs postoperatively after major surgery
48-72 hours
MKSAP 20
DOACs are Direct Oral Anticoagulants, and timing for resumption is critical to balance bleeding risk and thromboembolism.
Essential geriatric prescribing principle
Frequent review of medication necessity
MKSAP 20
This principle helps to minimize polypharmacy and adverse drug reactions in older adults.
Rapid-acting depression treatment useful at end of life
Methylphenidate
MKSAP 20
Methylphenidate can provide quick relief of depressive symptoms in terminally ill patients.
Prophylactic device for pressure injury
Advanced static mattress or mattress overlay
MKSAP 20
These devices help redistribute pressure and prevent pressure ulcers in at-risk patients.
Genetic testing before prescribing allopurinol
HLA-B*58:01
MKSAP 20
Testing for this allele helps predict the risk of severe hypersensitivity reactions to allopurinol.
AHA-recommended number of hours of sleep in adults
7
MKSAP 20
The American Heart Association emphasizes adequate sleep for cardiovascular health.
Indication for one-time abdominal aortic aneurysm screening
Men aged 65-75 years who have ever smoked
MKSAP 20
This population is at increased risk for abdominal aortic aneurysms.
Systems factors that contribute to diagnostic error
Communication policies and practices, resources, practice structure
MKSAP 20
These systemic issues can lead to failures in diagnosis and patient care.
Contributors of suboptimal care transitions
Poor communication among team; inadequate information transfer and patient education
MKSAP 20
Effective transitions are critical for continuity and quality of care.
Perioperative management of chronic β-blocker therapy
Continue β-blocker unless prohibited by hypotension
MKSAP 20
Maintaining β-blockers can help prevent cardiovascular complications during surgery.
Likely the greatest indicator of health outcomes
Socioeconomic position
MKSAP 20
Socioeconomic factors significantly influence overall health and access to care.
Indications for deferral of surgery in patients with hypertension
Evidence of end-organ dysfunction or BP >180/110 mm Hg
MKSAP 20
These conditions increase the risk of perioperative complications.
Role of preoperative placement of IVC filter in VTE prophylaxis
None
MKSAP 20
Current guidelines do not support the routine use of IVC filters for VTE prophylaxis before surgery.
Role of adding aspirin for primary prevention of ASCVD in a patient aged >59 years
None
MKSAP 20
Aspirin is not recommended for primary prevention in this age group due to risk of bleeding.
Nutrition factors predictive of poor surgical outcomes
15% weight loss over 6 months, BMI <18.5, serum albumin level <3.0 g/dL (30 g/L)
MKSAP 20
These indicators reflect nutritional status and can influence surgical recovery.
Initial preoperative assessment of patients with ≥1% risk for MACE
Assessment of functional capacity
MKSAP 20
MACE stands for major adverse cardiac events.
Time to stop DOACs preoperatively
2-3 days before surgery
MKSAP 20
Impact of palliative medicine
Improved quality of life, symptoms, mood, and caregiver satisfaction
MKSAP 20
Basic principles of medical ethics
Beneficence, nonmaleficence, respect for patient autonomy, justice
MKSAP 20
Indication for preoperative urinalysis
Suspected UTI, planned urologic procedure
MKSAP 20
Lead-time bias
Survival time appears longer because the screened patient was diagnosed earlier
MKSAP 20
Self-reflection and discovery to build honesty and trustworthy relationships
Cultural humility
MKSAP 20
USPSTF-recommended BP screening frequency in adults aged ≥40 years
Annually
MKSAP 20
Prevalence of U.S. adults who use vitamins or dietary supplements
50%
MKSAP 20
USPSTF-recommended means of calculating CV risk
Pooled Cohort Equations
MKSAP 20
Elderly fall prevention interventions
Exercise, discontinuing/decreasing centrally acting medications, modifying home environment
MKSAP 20
Most common type of preventable medical error
Medication errors (prescribing/transcribing, dispensing, administering/taking, or monitoring)
MKSAP 20
Tdap vaccination recommendation for pregnant patients
Between 27 and 36 weeks’ gestation for every pregnancy
MKSAP 20
Treatment of established pressure injuries
Wound care, protein supplements, pressure-reducing surfaces, hydrocolloid and foam dressings
MKSAP 20
Postoperative transfusion threshold in orthopedic and cardiac surgery patients
Hemoglobin level of 8 g/dL (80 g/L)
MKSAP 20
Mnemonic for never events in health care
WSPEs (wrong-site, wrong-procedure, wrong-patient errors)
MKSAP 20
Indication for one-time screening for hepatitis C
All patients aged 18-79 years
MKSAP 20
Indication for preoperative echocardiography in patients with valvular disease
Moderate to severe valve disease without TTE within last year or change in clinical status
MKSAP 20
Population-based screening for carotid artery stenosis
USPSTF grade D
MKSAP 20
Indications for cardiac catheterization before noncardiac surgery
Same as those for patients not undergoing surgery
MKSAP 20
Routine preoperative laboratory testing in low-risk surgery (cataract surgery, hernia repair)
None
MKSAP 20
Length-time bias
Survival time appears longer because screening detects indolent disease
MKSAP 20
Indication for screening for chlamydia and gonorrhea in women
Age ≤24 years and sexually active
MKSAP 20
Screening for CAD in low-risk asymptomatic patients
None
MKSAP 20
Timing of palliative medicine initiation for incurable/advanced disease
At time of diagnosis
MKSAP 20
Threshold functional capacity for proceeding to surgery without further testing
4 METs
MKSAP 20
METs refers to Metabolic Equivalent of Task, a measure of exercise capacity.
Structured communication strategies to improve handoffs
I-PASS, call-outs, SBAR, check-backs
MKSAP 20
These strategies are designed to enhance communication and reduce errors during patient handoffs.
Test’s ability to identify those without the disease
Specificity
MKSAP 20
Specificity is a key concept in diagnostic testing, indicating the proportion of true negatives.
Ethical distinction between withholding and withdrawing care
None
MKSAP 20
This indicates that there is no ethical difference between the two actions in medical practice.
Age to begin osteoporosis screening in average-risk women
65 years
MKSAP 20
This recommendation is based on guidelines for osteoporosis prevention.
Recommended frequency of Td booster in adults
Every 10 years
MKSAP 20
Td refers to Tetanus and Diphtheria vaccination.
Population appropriate for depression screening
All adults, including pregnant and postpartum patients
MKSAP 20
This highlights the importance of mental health screening across various demographics.
Minimum preoperative DAPT duration after drug-eluting stent placement
3-6 months
MKSAP 20
DAPT refers to Dual Antiplatelet Therapy, crucial for preventing thrombotic events.
Indications for perioperative bridging anticoagulation in patients with AF
CHA2DS2-VASc ≥7, recent thromboembolic event, mechanical heart valve
MKSAP 20
These criteria help assess the risk of thromboembolism in atrial fibrillation patients.
Pneumococcal vaccination for immunocompetent patients aged ≥50 years
PCV20 alone, PCV21 alone, or PCV15 followed by PPSV23 ≥1 year later
MKSAP 20
PCV refers to Pneumococcal Conjugate Vaccine, and PPSV23 refers to Pneumococcal Polysaccharide Vaccine.
Hospital VTE prophylaxis following hip fracture or total knee/hip arthroplasty
Concomitant mechanical and pharmacologic prophylaxis
MKSAP 20
This approach reduces the risk of venous thromboembolism in surgical patients.
Effect of behavioral counseling interventions on cardiovascular events
20% reduction
MKSAP 20
This statistic reflects the efficacy of counseling in promoting heart health.
Calculation for number needed to treat
1/absolute risk reduction
MKSAP 20
This formula helps determine the effectiveness of a treatment.
Targeted screening in high-risk patients
Case finding
MKSAP 20
This strategy focuses on identifying patients who may benefit from screening based on risk factors.
Preoperative laboratory testing in patients with CKD
Serum electrolyte and creatinine levels
MKSAP 20
CKD refers to Chronic Kidney Disease, making these tests vital for surgical safety.