Innate Immunity and WBC Flashcards
1
Q
What is he process by which leukocytes exit the bloodstream and migrate into tissues, in response to inflammation or infection?
A
Leukocyte extravasation
2
Q
What cells are recruited in Extravasation?
A
Selectins
Integrins
3
Q
What is the role of selectins?
A
Bind carbohydrates on leukocytes
4
Q
What are integrins involved in?
A
Cell adhesion, found on leukocytes
5
Q
In addition to activating phagocytes, what else do PAMPs do?
A
Activate the complement system
6
Q
What are the 3 roles of the complement system?
A
Inflammation
Cell lysis
Opsonisation
7
Q
What are the 3 complement activation pathways?
A
Classical
Alternative
Lectin
