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Immunology > Antibody-Mediated/Humoral Immunity > Flashcards

Antibody-Mediated/Humoral Immunity Flashcards

1
Q

What are Streptococcus pneumonia, vibrio cholera, and Neisseria gonorrhoea examples of?

A

Extracellular bacterial pathogens

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2
Q

What are worms an example of?

A

Extracellular parasitic pathogen

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3
Q

What can antibodies only attach to?

A

Their specific antigen

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4
Q

What are antibodies produced by?

A

B lymphocytes

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5
Q

What immunoglobin has a monomeric and dimeric form?

A

IgA

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6
Q

What immunoglobin is secreted later in the primary response and is the main antibody calss in the secondary response?

A

IgG

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7
Q

What is the first antibody class secreted in the primary response?

A

IgM

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8
Q

What antibody exists as a dimer in secretions via J-chain?

A

IgA

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9
Q

Which immunoglobin is primarily involved in allergic reactions?

A

IgE

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10
Q

Which immunoglobin is the most common circulating antibody isotope and can be transferred through the placenta?

A

IgG

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11
Q

Which antibody is the most important in protecting against gut infections?

A

IgA

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12
Q

Which antibody is most abundant in body fluids?

A

IgG

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13
Q

Which antibody is predominantly present in breast milk and colostrum?

A

IgA

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14
Q

What is the first antibody expressed on a B cell?

A

IgM

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15
Q

Which antibody binds to FcεR1 on mast cells?

A

IgE

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16
Q

Which antibody binds to FcγR on macrophages?

A

IgG

17
Q

Which antibody is mainly secreted from mucosal surfaces?

A

IgA

18
Q

Which antibody is a pentamer?

A

IgM

19
Q

Why are T-independent responses fast?

A

Because B cells are directly activated by antigens with certain types of structure

19
Q
A
20
Q

What is the only antibody class that can be produced in T-independent response?

A

IgM

21
Q

Humoral immunity is mediated by…?

A

B cells

22
Q

Humoral immunity is also known as?

A

Antibody-mediated immunity

23
Q

what happens to B cells upon activation by antigens?

A

Undergo clonal selection followed by clonal expansion

Immunology (16 decks)

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