Immunodeficiency Flashcards
What is inherited genetic defect in the immune system?
Primary immunodeficiency
What is loss immune function due to exposure from an external agent?
Secondary (acquired) immunodeficiency
What are examples of secondary immunodeficiency?
Acquired Immunodeficiency Syndrome (AIDS)
Human Immunodeficiency Virus (HIV)
What cells are a major source of HIV replication and eventually killed by the virus?
CD4 T cells
Which bodily fluids can HIV be trasmitted by?
Urine
Rectal fluids
Semen
Blood
gp120, gp41, lipid bilayer, and trimer spikes are all components of what?
HIV Retrovirus
Antibodies are important in tackling HIV, what part of antibody binds to which part of antigen?
Variable region of antibody binds to epitope of antigen
When HIV is trasmitted via sharing of needles, what cell types are involved in initial protection at the site of infection?
Epithelial, macrohpages, and neutrophils
True or false. Activiated CD4 T cells are the major source of HIV replication, these calls are eventually killed by the virus = severe immunodeficiency
True