Immunodeficiency Flashcards

1
Q

What is inherited genetic defect in the immune system?

A

Primary immunodeficiency

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2
Q

What is loss immune function due to exposure from an external agent?

A

Secondary (acquired) immunodeficiency

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3
Q

What are examples of secondary immunodeficiency?

A

Acquired Immunodeficiency Syndrome (AIDS)
Human Immunodeficiency Virus (HIV)

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4
Q

What cells are a major source of HIV replication and eventually killed by the virus?

A

CD4 T cells

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5
Q

Which bodily fluids can HIV be trasmitted by?

A

Urine
Rectal fluids
Semen
Blood

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6
Q

gp120, gp41, lipid bilayer, and trimer spikes are all components of what?

A

HIV Retrovirus

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7
Q

Antibodies are important in tackling HIV, what part of antibody binds to which part of antigen?

A

Variable region of antibody binds to epitope of antigen

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8
Q

When HIV is trasmitted via sharing of needles, what cell types are involved in initial protection at the site of infection?

A

Epithelial, macrohpages, and neutrophils

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9
Q

True or false. Activiated CD4 T cells are the major source of HIV replication, these calls are eventually killed by the virus = severe immunodeficiency

A

True

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10
Q
A
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