Inflammatory Bowl Disease

Question 1

what are the diagnostic tests done in crohn’s?

Answer 1

endoscopy and colonoscopy (just like in FAP)

Question 2

what is the artery supplying the ascending colon, ileocolic part and transverse colon

Answer 2

superior mesenteric artery (R. colic a., Middle colic a., and ileocolic a.)

Question 3

what is the artery supplying the descending colon, sigmoid and rectum

Answer 3

inferior mesenteric a. (L.colic a., sigmoid a., superior rectal a.)

Question 4

which disease is described as continuous proximal inflammation of the colon mainly the rectum and sigmoid affecting the mucosa and submucosa; left colon involvement> R.colon
-men=women
-pancolitis 30-50% of pt
-spreads proximally from the rectum

Answer 4

ulcerative colitis

Question 5

which disease has the following morphology;
-cryptic abscess is specific to this dis
-mucosa is granular, edematous, fragile, & ulcerated
-continuous, uninterrupted involvement
-disappearance of haustra
-column &Meso shorten?

Answer 5

ulcerative colitis

Question 6

what are the clinical presentation of ulcerative colitis?

Answer 6

abdominal pain
mucus discharge
pain
chronic bloody diarrhea

Question 7

what are the diagnostic tests done for ulcerative colitis?

Answer 7

-rectal exam then colonoscopy
-Lab; leukocytosis, C-reactive protein (inc), sedimentation (inc)
-stool sample
-perinuclear antineutrophil cytoplasmic antibody (p-ANCA)

Question 8

which complication is specific for crohn’s?

Answer 8

stenosis(narrowing)

Question 9

which complication is specific for UC?

Answer 9

cryptic abscess

Question 10

what do you see in UC while doing endoscopy

Answer 10

no vascularization
bleeding
fragile mucosa

Question 11

what are the complications in UC? oral

Answer 11

-fissure
-fistula
-abscess
-bleeding
-incontinence
-colon perforation due to fulminant colitis
-dysplasia and colon ca [3% risk for 1st 10yrs, then 1-2% risk for each yr after that]