Hemostasis And Surgical Bleeding -merter

Question 1

Endothelial cells secrete ….. and …… for vasodilation

Answer 1

Prostacyclin (PGI2) and nitric oxide

Question 2

Endothelin makes ….

Answer 2

Vasoconstriciton

Question 3

Which proteins are vasodilators?

Answer 3

• Prostacyclin (PGI2)
• Nitric oxide

Question 4

Which proteins are vasoconstrictors?

Answer 4

• Endothelin
• Tromboxane A2 (TXA2)
• Serotonin

Question 5

What are the Hemostasis steps?

Answer 5

1)vascular spasm (vasoconstriciton)

2)Primary hemostasis(platelet plug formation)

3)secondary hemostasis(clot formation)

4)anticoagulant & thrombolysis

Question 6

Which cells trigger intrinsic factors(coagulation factors)?

Answer 6

When tissue damage occur SUBENDOTHELIAL COLLAGEN exposed to the blood and triggers coagulation factors we call it intrinsic pathway

Question 7

Which cells activate extrinsic facotrs?

Answer 7

Endothel secretes tissue factor (thromboplastin) activates extrinsic pathway

Question 8

Anticoagulants are given before surgery to pt with risk of thrombosis

Question 9

What is the most commonly used anticoagulant?

Answer 9

Low-molecular-weight heparins (LMWHs) Derived from unfractionated heparin

Question 10

What are examples of Low-molecular- weight heparins (LMWHs)
Anticoagulants?

Answer 10

-parin
(Bemiparin
Certoparin
Deltaparin
Enoxaparin)