Inflammatory Arthritis Flashcards
What are the 3 types of inflammatory arthritis?
Rheumatoid factor RA. Undifferentiated inflammatory arthritis. Spondyloarthritis.
What is the difference between rheumatoid arthritis and spondyloarthritis?
RA is a type of inflammatory arthritis where the majority of people will have
a positive rheumatoid factor and cyclic citrullinated peptide (CCP). For this
reason, it is often referred to as seropositive arthritis.
The clinical conditions known as Spondyloarthritis (SpA), on the other hand, are types
of inflammatory arthritis where people do not have antibodies in their blood. For this
reason, spondyloarthritis is known as seronegative SpA or seronegative arthritis.
How is rheumatoid arthritis identified in the blood?
Using rheumatoid factor (RhF). Cyclic citrullinated peptide (CCP). 20% are seronegative however!
What are the two types of spondyloarthritis?
Axial SpA e.g. ankylosing spondylitis, non radiographic axial SpA.
Peripheral SpA e.g. psoriatic arthritis, enteropathic arthritis, reactive arthritis, juvenile onset SpA.
Give 3 symptoms of ankylosing spondylitis.
Chronic lower back pain. Buttock/hip/neck pain. Night pain. Morning stiffness. Peripheral arthritis. Enthesitis (inflammation where tendon inserts into bone). Dactylitis (inflammation of the entire toe/finger).
What is meant by a pannus?
Pannus is an abnormal layer of fibrovascular tissue or granulation tissue. Common sites for pannus formation include over the cornea, over a joint surface (as seen in rheumatoid arthritis),
Name 2 clinical features of psoriatic arthritis.
Peripheral arthritis. Axial disease. Enthesitis. Dactylitis. Skin and nail disease. Arthritis mutilans.
What are the three types of psoriatic arthritis?
Polyarticular (involvement of many small joints in hands and feet).
Oligoarticular (affects a few large joints e.g. knees, ankles, elbows).
Spondyloarthritis (involvement of sacroiliac joints and spine).
What is meant by arthritis mutilans?
Severe inflammation damaging the joints in hands and feet - deformation and problems with moving the affected area.
What is meant by reactive arthritis?
Condition causing redness and swelling of joints, usually after an infection.
What is Enteropathic arthritis?
Enteropathic arthritis, or EnA, is a form of chronic, inflammatory arthritis associated with the occurrence of an inflammatory bowel disease (IBD), the two best-known types of which are ulcerative colitis and Crohn’s disease..
Name 3 signs of reactive arthritis.
Peripheral arthritis. Enthesitis. Dactylitis. Axial (lower back pain). Extra-articular problems (outside the joint) e.g. ocular - conjunctivitis, GU - dysuria, GI - diarrhoea, oral lesions, nail changes, skin lesions.
