Infertility & assisted conception Flashcards

1
Q

What infections are checked for prior to assisted conception treatment?

A

Rubella

BBVs (Hep B/C, HIV)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How do you assess ovulation?

A

Progesterone Day 21

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How is intrauterine insemination performed?

A

Prepared semen inserted into uterine cavity around time of ovulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

In IVF what is used to down regulate prior to the baseline scan?

A

Synthetic gonadotrophin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How are the ovaries stimulated in IVF?

A

H containing gonadotrophins (FSH +/- LH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the purpose of the action scan in IVF?

A

To assess response to FSH
Assess for risk of OHSS
Plan date/timing of HCG injection (mimics LH)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the main concerning complication of IVF?

A

Ovarian HyperStimulation Syndrome (OHSS)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How does OHSS present?

A

Abdo pain/bloating
Nausea
Diarrhoea
Breathlessness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How is OHSS treated?

A

if before transfer ‘coasting.elective freeze

If after mnitor,anti-thrombotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the current success rates for IVF?

A

35%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which embryological ducts go onto form the repro tract in males?

A

Wolfian ducts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Which embryological ducts go onto form the repro tract in females?

A

Mullerian ducts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What causes androgen insensitivity syndrome?

A

Androgen induction of Wolfian duct does not occur

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How is cryptorchidism treated?

A

Orchidoplexy if <14 y/o (to reduce cancer risk)

If an adult consider orchidectomy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What cells produce testosterone?

A

Leydig cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What do sertoli cells secrete?

A

Inhibin & activin

Secrete androgen binding globulin

17
Q

What does inhibin do?

A

Regulates FSH secretion & controls spermatogenesis

18
Q

What does testosterone inhibit?

A

GnRH & LH

19
Q

What are the functions of dihydrotestosterone?

A

Enlargement of male sex organs
Secondary sexual characteristics
Anabolism

20
Q

What is thefunction of the epididymis & vas deferens?

A

Exit route from testes to urethra
Concentrate & store sperm
Sperm maturation

21
Q

What is the function of theseminal vesicles?

A

Produce sperm into ejaculatory duct
Supply fructose
Secrete prostaglandins (stimulates motility)
Secrete fibrinogen

22
Q

What is the function of the prostate gland?

A

Produce alkaline (neutralise vagina) Produces clotting enzymes to clot semen within females

23
Q

What is the function of the bulbourethral glands?

A

Lubricant

24
Q

What are obstructive causes of male infertility?

A

CF
Vasectomy
Infection

25
Q

What hormones are checked in a male infertility screen?

A
LH 
FSH 
Testosterone 
PRL
TSH