Infectious Disease I Flashcards
Peak incidence of otitis media
6-36 months
Most common bugs of otitis media
s. pneumo, h.flu, m. cat
First line therapy for otitis media
amoxicillin
Treatment of otitis media if failure of first line
Augmentin
Complications of otitis media
mastoiditis, venous sinus thrombosis, brain abscess
Key points regarding the effect of abx when treating otitis media
Abx decrease duration of infection but do NOT decrease incidence of complications
Main bacteria with otitis externa
pseudomonas, s. aureus, proteus
Sx include: Otalgia, Pain at tragus or when auricle is pulled!!!!! Pruritis, Discharge, Hearing loss
otitis externa
PE findings include: Edematous and erythematous ear canal. May see yellow, brown, white or grey debris
otitis externa
Tx of otitis externa
irrigate gently w/1:1 dilution of 3% hydrogen peroxide AT BODY TEMP.
Tx of inflammation associated with otitis externa
Cortisporin, Cipro HC, Tobradex
soln if unsure if TM is intact
Most common cause of pharyngitis/tonsillitis in children 2-5 yrs
virus
Most common bacterial cause of pharyngitis/tonsillitis
streptococcus pyogenes (GABHS)
Sx include: rhinorrhea, cough, mild pharyngitis, fatigue, anorexia, abdominal pain
viral pharyngitis
Sx include: beefy red tonsils with exudate, tender anterior cervical lymphadenopathy, fever, HA, abdominal pain
GABHS pharyngitis
Diagnostic method of choice for GABHS
throat culture
Abx treatment for GABHS pharyngitis
PCN first line. Macrolides as alternative
Sx include: malaise, beefy red tonsils/exudate, posterior cervical adenopathy, splenomegaly, afebrile
Epstein-Barr virus
Diagnostics for EBV
heterophile antibody test (Monospot). EBV antibodies on CBC (IgG, IgM)
How long should a pt with EBV avoid contact sports?
6-8 weeks
Caused by enterovirus. High fever and small ulcers on erythematous base on tonsillar pillars, soft palate, and uvula
Herpangina
caused by coxsackie virus. Vesicles or red papules found on the tongue, oral mucosa, hands, and feet. Mild fever and malaise
hand, foot, and mouth disease
Occurs in unimmunized child (HIB), High fever, sore throat, stridor, Drooling and respiratory distress
epiglottitis
one to several small ulcers on the insides of lips or elsewhere in the mouth. Last 1-2 weeks
Aphthous Stomatitis (Canker Sore)
Caused by Herpes Simplex. Ulcers in the mouth, Fever, Tender cervical lymphadenopathy. Lasts 7-10 days
Gingivostomatitis
Mainly affects infants or older children in debilitated state
May occur in patients taking broad spectrum antibiotics or steroids
oral candidiasis (thrush)
Sx include: mouth soreness, refusal of feedings. PE reveals white curd-like plaques predominantly on buccal mucosa
oral candidiasis (thrush)
Treatment for oral candidiasis (thrush)
Nystatin oral suspension
viral URI symptoms persist beyond 10-14 days. patient starts to improve and then becomes worse. Sx include: facial pain, maxillary teeth pain, malodorous breath
sinusitis
infectious disease that is rare before age 10 years
sinusitis
Infection causing inflammation of the larynx, trachea and bronchi. Most often caused by parainfluenza virus. Presents 6months to 3 yrs of age
Croup (laryngotracheobronchitis)
Sx include: URI symptoms with barking cough and stridor. Absent or low grade fever
Croup (laryngotracheobronchitis)
Tx of croup
Dexamethasone 0.6mg/kg IM one dose
Tx of croup if stridor at rest
Oxygen, nebulized racemic epinephrine. If symptoms resolve in 3 hours can be safely discharged. Otherwise hospitalize
Pathogen that most commonly causes epiglottitis
h. flu type B
Sx include: fever, dysphagia, drooling, “hot potato” voice, inspiratory retractions, soft stridor
epiglottitis
Xray finding for epiglottitis vs croup
epiglottitis = thumbprint sign. croup = steeple sign
Sx include: parotid gland swelling common, aseptic meningitis, transient pancreatitis, orchitis or oophoritis, epididymitis
Mumps
Vasculitis of unknown etiology affecting medium sized arteries. Occurs almost exclusively in pediatric population
kawasaki disease
Typical lab results for kawasaki disease
hypoalbuminemia, thrombocytosis, and elevated ESR
Sx include: rash, mucous membrane involvement, unilateral cervical adenopathy, nonpurulent conjunctivitis, swollen hands and feet
kawasaki disease
Most serious complications from kawasaki disease
Coronary vasculitis and aneurysm formation
Leading cause of acquired heart disease in children in the US and Japan
Kawasaki disease
Tx of Kawasaki disease
High-dose Aspirin and 2 days of IV immunoglobulin
tiny white dots on a red base appearing on buccal mucosa 1 or 2 days prior to onset of rash
Koplik spots (pathognomic for rubeola-measles)
Most important reason we vaccinate for rubella (German measles)
prevent spread to pregnant women to avoid congenital rubella syndrome
Most common complications of rubella (German measles)
arthritis and arthralgia
Results from HHV-6. Abrupt onset of high fever which lasts for 3-7 days. Resolution of fever is followed by development of erythematous maculopapular rash
Roseola
Caused by Parvovirus B19. Rash is flat, lacy, reticular, often pruritic, located on cheeks, trunk, and extremities. Children are NOT contagious once the rash appears
5th disease
Generalized pruritic vesicular rash beginning on face, neck, or upper trunk and spreads outward with lesions at different stages (dew drop on rose petal)
varicella (chickenpox)
How long is chickenpox contagious?
from 1-2 days prior to onset until the lesions have crusted
First sign is “herald patch.” Followed by lesions that are oval with “christmas tree” appearance.
Pityriasis Rosea
Inflammatory process of the smaller lower airways, usually caused by RSV. Can progress to respiratory failure and is potentially fatal
Bronchiolitis
Sx include: fever, URI sx, tachypnea, wheezing
Bronchiolitis
URI symptoms with cough and malaise. Coarse bronchial sounds. WBC normal, CXR clear. Most of the time it is viral
bronchitis
Tx of pneumonia in kids
abx, fluids, O2
Dangerous component of pertussis (whooping cough)
small infant can die from respiratory distress
starts as URI symptoms and slight fever may be present, cough is initially. After about 2 weeks, coughs become paroxysmal with classic “whoop”
pertussis (whooping cough)
Characterized by abnormal dilation and distortion of the bronchial tree, resulting in chronic obstructive lung disease
bronchiectasis
Most common cause of bronchiectasis in developed nations
cystic fibrosis
Abx treatment for pertussis
Erythromycin for 14 days
Azithromycin for 5 to 7 days