Infection in Pregnancy Flashcards
How does CMV present in immunocompetent patients?
Asymptomatic
or mild flu-like illness
How does mononucleosis syndrome present?
Fever
Splenomegaly
Impaired liver function
How is CM investigated?
Serology for CMV IgM and IgG
What is the recommended treatment for pregnant women with CMV?
None (assuming immunocompetence)
How may foetal CMV be diagnosed?
Amniocentesis
What do babies with CMV tend to develop?
Sensorineural hearing loss
Psychomotor development delay
Visual impairment
What are the risk factors for group B strep infection in the baby?
Prematurity
Rupture of membranes >24hrs before delivery
Pyrexia during labour
How may group B strep infection manifest in mother?
UTI
Chorioamnionitis
Endometritis
How does chorioamnionitis present?
Fevers
Lower abdo and uterine tenderness
Discharge
Foetal tachycardia
How does endometritis present?
Fevers
Lower abdo pain
Intermenstrual bleeding
Foul discharge
How is group B strep infection diagnosed?
Vaginal and rectal swab
Urine culture
How is group B strep infection treated?
Penicillin
What prophylaxis is given to pregnant women who have risk factors for group B strep?
Penicllin
What can parovirus 19 cause if transmitted to foetus?
Miscarriage
Intra-uterine death
How does parovirus in adults tend to present?
Asymptomatic
Maybe symmetrical arthalgia
How does parovirus 19 present in kids?
URTI Malaise Headaches Fever Erythema infectiosum
What is erythema infectiosum?
Maculopapular rash sparing nose, eyes and mouth
Slapped cheek syndrome
What is the most common manifestation of foetal parovirus 19?
Foetal hydrops
Rubella vaccine cannot be given in pregnancy true/false
True - it is a live virus
How does rubella present?
Asymptomatic
Non-specific - malaise, headache, rash, lymphadenopathy
What kind of rash is found in rubella?
Fine maculopapular
What is the risk of transferring rubella to the foetus before 12 weeks?
90%
What is the likelihood of transferring rubella to the foetus over 20 weeks?
45%
What is the classic rash found in varicella zoster infection?
Pruritic maculopapular rash
What is the incubation period of varicella-zoster?
10-21 days
When is the infectious period of varicella zoster?
48 hours prior to rash until vesicles crusted over
What can a pregnant woman who comes into contact with varicella zoster be given prophylactically?
Varicella zoster immunogloublin
What is given in varicella zoster infection in pregnancy?
Aciclovir
What is the follow up to varicella zoster infection in pregnancy?
USS 5 weeks later (to check for foetal abnormality)
