Breast Week - Anatomy Flashcards

1
Q

What is the secretory tissue of the breast made of?

A

Lobes

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2
Q

What do the lobes of the breast contain?

A

compound tubulo-acinar gland

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3
Q

What does the compound tubuloacinar gland drain into?

A

Ducts which lead to the nipple

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4
Q

What separates the breast tissue into lobules?

A

Fibrous tissue

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5
Q

What are the suspensory ligaments of the breast?

A

Thick condensations of connective tissue extending from dermis to deep fascia over muscle

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6
Q

What is the basic functional unit of the breast?

A

terminal duct lobular unit

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7
Q

What does TDLU pass into in the non-lactating breast?

A

Intralobular collecting duct

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8
Q

Where does the intralobular collecting duct drain into?

A

Lactiferous duct

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9
Q

Where does the lactiferous duct lead to?

A

Nipple

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10
Q

What separates the acini of the breast?

A

Loose connective tissue

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11
Q

What are the secretory cells of the acinus surrounded by?

A

Myoepithelial cells

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12
Q

Describe the epithelium of the nipple?

A

Keratinised stratified squamous epithelium

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13
Q

Describe the core of the nipple

A

Irregular connective tissue mixed with smooth muscle bundles

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14
Q

Describe the lining of the nipple near the surface

A

Stratified squamous

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15
Q

Describe the changes that occur in the breast during the luteal phase of menstruation

A

Epithelial cells get taller
lumen of ducts is enlarged
Small secretions in ducts

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16
Q

What changes occur in the breast during the first trimester?

A
Elongation and branching of smaller ducts
Cell proliferation (of epithelial cells of glands and myoepithelium cells)
17
Q

What changes occur in the breast during the second trimester?

A

Glandular tissue develops with differentiation

Plasma cells and lymphocytes infiltrate nearby tissue

18
Q

What changes occur during the breast during the third trimester?

A

Secretory alveoli continue to mature with development of extensive rER

19
Q

Describe the composition of human milk

A
Mostly water
1.5% protein
7% carbs
3.5% lipid
Ions, vits and IgA
20
Q

Describe apocrine secretion in the breast

A

Lipid droplets secreted surround by a membrane with a small amount of cytoplasm

21
Q

Describe mesocrine secretion in the breast

A

Proteins secreted in vesicles which merge with membrane and only release contents into duct system

22
Q

What is mesocrine secretion otherwise known as?

A

Exocytosis

23
Q

Where are the proteins in human milk made?

A

rER

24
Q

What changes occur in the breast following menopause?

A

Less collagen and elastic fibres

Secretory cells degenerate