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POS 2022 > Infection et ATB > Flashcards

Infection et ATB Flashcards

1
Q

Anaérobe + commun dans colon

A

Bacteroides fragilis

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2
Q

dérobe plus commun dans colon

A

E.coli

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3
Q

Dx C.diff

A

EXOToxine A ELISA (baccille gram +)

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4
Q

KT sepsis: germe plus fréquent (3)

A

75% gram+
#1 Staph epidermis
#2 Staph aureus
#3 Enterocoque

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5
Q

KT sepsis ATB empirique

A

Vanco vu staph epidermidis 80% resistant cloxa

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6
Q

The most common cause of cellulitis

A

is beta-hemolytic streptococci (groups A, B, C, G, and F), most
commonly group A Streptococcus or Streptococcus pyogenes

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7
Q

The most common cause of skin abscess

A

is S. aureus

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8
Q

what can cause lymphangitis

A

Strep pyogenes can cause lymphangitis (puss in lymphatics = pyogenes)

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9
Q

Infection nécrosantes 3 germe plus fréquent

A

Strep A et SARM (exotoxine)
Clostridium (alpha toxine)

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10
Q

Peritonite bactérienne spontanée germe plus fréquent

A

E.coli
Monobactérienne majorité temps

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11
Q

ATB pour gangrene gazeuse (1)

A

PNC

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12
Q

ATB de choix pour péritonite bactérienne spontané

A

Ceftri
et en prophylaxie après un épisode: ipro, TMP-SMX

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13
Q

Tx HCV

A

Ribavirin + sofosbuvir

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14
Q

manifs
extra-­‐hépatiques
du
VHC

A

:
cryoglobulinémie,
lymphome,
GN
membranoproliférative,
thyroïdite,
porphyrie,
lichen
plan,
diabèt

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15
Q

Cause #1 infection transplante et Tx

A

CMV
Tx: Ganciclovir

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16
Q

Localisation plus fréquente pneumonie aspi

A

segment superieur LID

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17
Q

Arthrite septique ATB empirique en attendant culture (2)

A

Ceftri+vanco

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18
Q

Arthrite septique germe #1 enfant et adulte

A

S. Aureus

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19
Q

Arthrite septique germe retrouve si anémie falciforme

A

salmonelle

20
Q

Arthrite septique germe retrouve chez UDIV ou pt avec malpeforant plantaire

A

Pseudomonas

21
Q

Endocardite germe #1

A

Staph
si UDIV pensé à pseudo

22
Q

Choc toxique germe plus souvent en cause

A

Staph aureus (exotoxine)

23
Q

ATB qui couvre pseudo (5)

A

Tazo
Ceftazidime
Cipro
Genta/tobra
Ok mais ont de la résistance: imipenem et méro

24
Q

Effets secondaire particulier ATB: Cipro

25
Q

Effets secondaire particulier ATB: Doxy

A

photosensibilit.

26
Q

Effets secondaire particulier ATB (2): Genta

A

nephrotoxique (réversible) et ototoxicité (irréversible)

27
Q

Effets secondaire particulier ATB Vanco (2)

A

leucopénie et néphrotoxique

28
Q

Effets secondaire particulier ATB Flagyl

A

neuropathie si usage liong terme

29
Q

ATB qui couvre anaérobe (6)

A

o Flagyl (couvre seulement les anaérobes, rien autre)

o Clinda: plus large spectre que flagyl
o Clavulin
o PNC
o Carbapénems
o Macrolide
(érythro,
clarithro,
azithro)

30
Q

ATB qui couvre PAS les BGN (3)

A

Vanco
Clinda
Ancef

31
Q

When to give antibiotics after drainage? (4)

A

• Patients with diabetes, cellulitis, signs of sepsis, bioprosthetic hardware (e.g. mechanical valves,
hip replacements)

32
Q

Critère pour Surgical Site Infection (time)

A

criteria that define SSI as infection related to an operative procedure that occurs at or near the surgical incision within 30 days of
the procedure or within 90 days (up 1 year in some references) if prosthetic material is implanted at
surgery

33
Q

Wound infection cmb ca nous prend GB pour dx dans notre culture

A

> 10E5 bacteria needed for wound infection, less if foreign body present

34
Q

Wound infection germe gram neg plus fréquent

35
Q

Wounds infection anaérobe plus fréquent

A

B. fragilis: #1 anaerobe in surgical wound infections

36
Q

ICU pneumonia germe plus fréquent (2)

A

ICU pneumonia: #1 S. aureus (gram + ) #2 pseudomonas (GRAM -), #3: E. Coli

37
Q

KT sepsis tx empiriquement avec banco mais quand on doit ajouté un antifongique d’amble?

A

Consider adding an antifungal agent if
o TPN, prolonged use of ATB, hematologic malignancy, transplant, femoral
catheterization, Candida spp colonization

38
Q

Tx empirique fascine nécrosante (3)

A

Méro/Tazo
Vanco
Clinda

39
Q

Gangrene Fournier gram ? monogram ou mixed organism

A

Mixed organisms (GPCs, GNRs, anaerobes)

40
Q

C.diff mécanisme action

A

Toxin B&raquo_space; toxin A
o Toxin B is essential for the virulence of C. difficile and is more than 10 times more potent
than toxin A on a molar basis for mediating colonic mucosal damage. Thus, strains
lacking toxin A can be as virulent as strains with both toxins

41
Q

ATB qui couvre ANA Gram + et Gram -

A

Mefoxin (cefoxitine)

42
Q

Causes de température PO?

A

1ères 48h: atélectasie, libération cytokines inflammatoires
2-5 jours: infx urinaire, pneumonie, TVP
> 5 jours: infection de plaie
Abcès se forme à partir de PO7 environ

43
Q

Tx pour HSV/EBV?

44
Q

Ce qui couvre SARM?

A

Vanco, linézolide

45
Q

ATB bactériostatiques?

A

MCS
Macro, clinda, suldfa

POS 2022 (14 decks)

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