Biologie cellulaire/immunologie/cytokines Flashcards

1
Q

Nommer les phases du cycle cellulaire en ordre

A

G0 - G1 - S - G2 - M

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2
Q

5 types de réactions immunologiques

A

1- Immédiat: IgE
2- Cytotoxique: complément, IgG
3- Complexes immuns: IgG, IgM, complexes immuns
4- Cellulaire: lymphocytes T

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3
Q

Autre nom pour cellules T helper?

A

CD4

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4
Q

Autre nom cellules T cytotoxiques?

A

CD8

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5
Q

Anticorps le plus gros?

A

IgM (MÉGA)

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6
Q

Anticorps le plus abondant?

A

IgG (traverse le placenta)

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7
Q

Anticorps pour réaction allergique?

A

IgE (parasites aussi)

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8
Q

Anticorps dans le lait maternel et salive et sécrétions GI?

A

IgA

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9
Q

Organes lymphoïdes primaires?

A

Os, foie, thymus

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10
Q

Organes lymphoïdes secondaires?

A

Ganglions, rate

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11
Q

CMH1

A

Virus et CD8

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12
Q

CMH2

A

Bactéries, CD4

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13
Q

LA phase la plus sensible à la radiothérapie?

A

M

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14
Q

LA phase la plus variable en terme de temps du cycle?

A

G1

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15
Q

Cytokines pro-inflammatoires?

A

1-2-6-8-INFy-TNF-PAF

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16
Q

Cytokines anti-inflammatoires?

A

4-10-13-15-TGFB-prostaglandines

17
Q

2 cytokines principales sécrétées lors injury/infection?

A

TNF alpha et IL-1

18
Q

Fx Épithélialisation?

A

PDGF, EGF, FGF

19
Q

Fx angiogénèse?

A

PDGF, EGF, FGF, IL-8

20
Q

Rôle TGFB?

A

Fibroplasie

21
Q

LE facteur de croissance clé dans la guérison des plaies?

A

PDGF (recrute et active les macrophages, produit TNFalpha et IL-1)

22
Q

TNF alpha responsable de quoi?

A

SIRS et MOF

Procoagulant, ce sont des macrophages

23
Q

IL-1?

A

Augmente la température corporelle

24
Q

Source d’histamine principale dans le sang et dans les tissus?

A

Blood: basophiles
Tissus: mastocytes

25
Q

Ordre d’apparition des hormones dans le cortex/médulla surrénales?

A

GIRLFRIEND (pour cortex)
Glomerulosa: minéralocortico (aldostérone)
Fasciculata: glucocortico (cortisol)
Réticulaire: sex (progest, andro, oesto)

Médulla: catécholamines