Indications/Nursing Consider/Med Names Lipid Meds Flashcards
Those who cannot tolerate statins should be on which lipid lowering meds? (2)
Cholesterol Absorption Inhibitors
PCSK9 Inhibitors
Lovera is which type of lipid lowering med?
Omega 3 fatty acid
Fenofibrate (Tricor) is which type of lipid lowering med?
fibrate
Which lipid lowering med is less effective as research does not support its efficacy in lowering cholesterol?
Niacin
What lipid lowering meds are first line tx?
Statins (HMG-CoA Reductase Inhibitors)
What lipid lowering meds can be given in combination with statins? (2)
cholesterol absorption inhibitors
PCSK9 inhibitors
Cholestyramine (Prevalite) is which type of lipid lowering med?
Bile acid sequestrant
What are the most effective and most prescribed lipid lowering drug?
Statins (HMG-CoA Reductase Inhibitors)
Vascepa is which type of lipid lowering med?
Omega 3 fatty acid
Ezetimibe (Zetia) is which type of lipid lowering med?
cholesterol absorption inhibitor
With statins, how is the risk of myopathy reduced?
by using the lowest effective dose
Which lipid lowering med was used for hyperlipidemia historically?
Niacin
What lipid lowering meds are sometimes used for secondary prevention after diet and exercise?
Statins (HMG-CoA Reductase Inhibitors)
What lipid lowering med is often reserved for people who have very high LDL levels?
PCSK9 inhibitors
Which type of lipid lowering med is Colesevelam (Welchol) ?
Bile acid sequestrant
What lipid lowering med should be taken at bedtime or in the evening? Why?
What are the exceptions?
Statins
Because cholesterol synthesis occurs while you are fasting, while you are sleeping so this is the best time to help block the cholesterol from forming
Rosuvastatin and Atorvastatin can be given in the morning
Espanova is which type of lipid lowering med?
Omega 3 fatty acid
Gemfibrozil (Lopid) is which type of lipid lowering med?
fibrate
Which lipid lowering med can be used together with fibrates?
bile acid sequestrants
Who should be on a statin? (5)
- Adults with a history of cardiovascular disease
- Those with LDL-C level of greater than 190 mg/dL
- Adults 40-75 years with diabetes
- Adults 40-75 years with LDL-C level of 70-189 mg/dL and a 5% to 19.9% 10-year risk of developing cardiovascular disease
- Adults 40-75 years with LDL-C level of 70-189 mg/dL and a 20% or greater 10-year risk of developing cardiovascular disease
What lipid lowering med is OFTEN given in conjunction with statins?
PCSK9 inhibitors
Which type of lipid lowering med is Colestipol (Colestid) ?
Bile acid sequestrant
What lipid lowering med start with a lower dose and increase as needed?
statins
What type of lipid lowering med is Alirocumab (Praulent) ?
PCSK9 Inhibitor
For what lipid lowering med will lipid panel usually be checked 4-6 weeks after starting the med? (2)
Statins
Fibrates
What lipid lowering meds may be used in pts with active liver disease?
Bile acid sequestrants
Serious liver problems are rare with which lipid lowering med?
statins
Fenofibric acid (Tripipix) is which type of lipid lowering med?
Fibrates
What type of lipid lowering med is Evolocumab (Repatha) ?
PCSK9 Inhibitors
Which lipid lowering med is safe for pregnant women?
Bile acid sequestrants
With statins, how is an increase in liver enzymes managed?
by reducing the dose or stopping until levels return to normal
What lipid lowering med is administered by SQ injection either weekly or monthly?
PCSK9 Inhibitors
why are bile acid sequestrants considered second line?
Because of drug-drug interactions
What is niacin made up of?
Nicotinic Acid and Vitamin B3
Which lipid lowering meds are not routinely used? (2)
Bile acid sequestrants
Niacin
When is niacin given?
at bedtime
Which lipid lowering meds have a strong record of efficacy and safety?
Bile acid sequestrants
Which lipid lowering med is often taken with an Acetylsalicylic acid (ASA) to help prevent flushing?
Niacin
For which lipid lowering meds are lipid levels checked every 3-4 months?
fibrates
