Mechanism of Actions Diabetes Meds

Question 1

What diabetes meds decrease absorption of carbohydrates? (2)

Answer 1

Metformin
Alpha Glucosidase Inhibitors

Question 2

What diabetes meds decrease appetite? (2)

Answer 2

Metformin
GLP-1 Receptor Agonists

Question 3

What diabetes meds stimulate beta cells to secrete insulin? (2)

Answer 3

Sulfonylureas
Meglitinides

Question 4

What diabetes meds decrease glucose production in the liver? (2)

Answer 4

Metformin
Sulfonylureas

Question 5

What diabetes meds improve how insulin works in the body and reduces insulin resistance? (2)

Answer 5

Thiazolidinediones
Metformin

Question 6

If a medication decreases the absorption of carbs, what is prevented?

Answer 6

glucose spikes

Question 7

What diabetes med delays the absorption of glucose in the small intestines? How?

Answer 7

​Alpha Glucosidase Inhibitors

By inhibiting alpha-glucosidase

Question 8

What diabetes meds increase insulin secretion? (5)

Answer 8

1. Sulfonylureas
2. GLP-1 Receptor Agonists
3. Meglitinides
4. DPP-4 Inhibitors
5. Amylin Analogues

Question 9

What diabetes med can help to decrease lipids?

Answer 9

Metformin

Question 10

What diabetes med inhibits reabsorption of glucose in the proximal renal tubules?

Answer 10

SGLT2 inhibitors

Question 11

What diabetes meds do not increase insulin secretion? (4)

Answer 11

1. Metformin
2. Alpha-Glucosidase Inhibitors
3. SGLT2 Inhibitors
4. Thiazolidinediones

Question 12

What diabetes med decreases platelet aggregation?

Answer 12

Metformin

Question 13

What diabetes med crosses the blood brain barrier? what does this do?

Answer 13

GLP-1 Receptor Agonists

This increases satiety

Question 14

What diabetes meds delay/slow gastric emptying? (3)

Answer 14

GLP-1 Receptor Agonists
DPP-4 Inhibitors
Amylin Analogues

Question 15

What diabetes med promotes glucose excretion in urine?

Answer 15

SGLT2 inhibitors

Question 16

What does delaying gastric emptying do?

Answer 16

helps regulate the postprandial rise in blood glucose / decreases glucose spikes

Question 17

What diabetes med slows glucose entry into the bloodstream? what does this do?

Answer 17

Alpha Glucosidase Inhibitors

This reduces postprandial glucose spikes

Question 18

What diabetes med reduces blood viscosity?

Answer 18

Metformin

Question 19

What diabetes med blocks hepatic gluconeogenesis?

Answer 19

​Thiazolidinediones

Question 20

What diabetes meds block glucagon secretion? (2)

Answer 20

GLP-1 Receptor Agonists
Amylin Analogues (suppresses postprandial glucagon secretion)

Question 21

What diabetes med promotes the growth and development of beta cells?

Answer 21

GLP-1 receptor agonists

Question 22

What diabetes med inhibit the dipeptidyl peptidase 4 enzyme? what does this enzyme do?

Answer 22

DPP-4 Inhibitors

This enzyme destroys the GI incretin hormones GLP-1 and GIP

Question 23

What diabetes med decreases glucagon secretion to decrease glucose production?

Answer 23

DPP-4 Inhibitors

Question 24

What diabetes meds provide renal protection? How?

Answer 24

SGLT2

by decreasing the protein loss and reducing the damage caused by hyper filtration

Question 25

what diabetes med allows incretin hormones to remain in circulation longer?

Answer 25

DPP-4 Inhibitors

Question 26

What diabetes meds increases the feeling of fullness or satiety? (2)

Answer 26

Amylin Analogues GLP-1 Receptor Agonists