Mechanism of Actions Diabetes Meds Flashcards
What diabetes meds decrease absorption of carbohydrates? (2)
Metformin
Alpha Glucosidase Inhibitors
What diabetes meds decrease appetite? (2)
Metformin
GLP-1 Receptor Agonists
What diabetes meds stimulate beta cells to secrete insulin? (2)
Sulfonylureas
Meglitinides
What diabetes meds decrease glucose production in the liver? (2)
Metformin
Sulfonylureas
What diabetes meds improve how insulin works in the body and reduces insulin resistance? (2)
Thiazolidinediones
Metformin
If a medication decreases the absorption of carbs, what is prevented?
glucose spikes
What diabetes med delays the absorption of glucose in the small intestines? How?
Alpha Glucosidase Inhibitors
By inhibiting alpha-glucosidase
What diabetes meds increase insulin secretion? (5)
- Sulfonylureas
- GLP-1 Receptor Agonists
- Meglitinides
- DPP-4 Inhibitors
- Amylin Analogues
What diabetes med can help to decrease lipids?
Metformin
What diabetes med inhibits reabsorption of glucose in the proximal renal tubules?
SGLT2 inhibitors
What diabetes meds do not increase insulin secretion? (4)
- Metformin
- Alpha-Glucosidase Inhibitors
- SGLT2 Inhibitors
- Thiazolidinediones
What diabetes med decreases platelet aggregation?
Metformin
What diabetes med crosses the blood brain barrier? what does this do?
GLP-1 Receptor Agonists
This increases satiety
What diabetes meds delay/slow gastric emptying? (3)
GLP-1 Receptor Agonists
DPP-4 Inhibitors
Amylin Analogues
What diabetes med promotes glucose excretion in urine?
SGLT2 inhibitors
What does delaying gastric emptying do?
helps regulate the postprandial rise in blood glucose / decreases glucose spikes
What diabetes med slows glucose entry into the bloodstream? what does this do?
Alpha Glucosidase Inhibitors
This reduces postprandial glucose spikes
What diabetes med reduces blood viscosity?
Metformin
What diabetes med blocks hepatic gluconeogenesis?
Thiazolidinediones
What diabetes meds block glucagon secretion? (2)
GLP-1 Receptor Agonists
Amylin Analogues (suppresses postprandial glucagon secretion)
What diabetes med promotes the growth and development of beta cells?
GLP-1 receptor agonists
What diabetes med inhibit the dipeptidyl peptidase 4 enzyme? what does this enzyme do?
DPP-4 Inhibitors
This enzyme destroys the GI incretin hormones GLP-1 and GIP
What diabetes med decreases glucagon secretion to decrease glucose production?
DPP-4 Inhibitors
What diabetes meds provide renal protection? How?
SGLT2
by decreasing the protein loss and reducing the damage caused by hyper filtration
what diabetes med allows incretin hormones to remain in circulation longer?
DPP-4 Inhibitors
What diabetes meds increases the feeling of fullness or satiety? (2)
Amylin Analogues
GLP-1 Receptor Agonists
