Immunology/Vaccines Flashcards
What is a vaccine?
A preparation that contains and infectious agent administered to create an immune response that will protect from an illness
What is immunology?
The process of rendering a subject immune or beck,ing immune by vaccination or exposure
What are some advantages of vaccinating?
Immunity long lasting, creates a memory response, boosting immune responses, inexpensive, is controlled exposure
Four necessities to be a vaccine.
Positively identify causative agent, immune response must protect against the disease, risk of vaccine must be lower than the risk of disease, should stimulate an immune response different than the disease response
What is a killed vaccine?
Dead virus or bacteria or pieces of microorganisms that cause a response
What is a subunit vaccine?
When only part of the microorganism is used
What is a modified live vaccine?
Microorganism that undergoes a process to become less dangerous
What is a live vaccine?
Full strength microorganisms given to not cause disease but still yield a response
What is a heterologous vaccine?
Microorganisms that are similar to target organism but does not cause the disease
What is a recombinant disease?
An unrelated organism that is injected with the DNA of the target organism to cause reshaping so it looks like the disease but does not cause disease
Advantages of killed vaccines?
Safe in pregnant animals, easy to store, unlikely to cause disease
Disadvantage of killed vaccines?
Less of an immune response that needs boosters
Pros of modified live vaccines?
Strong immunity, economically friendly
Disadvantages of micro live vaccines?
Capable of causing the disease, not safe in pregnant bitches, easily inactivate due to mishandling
Rules of vaccinating?
Never vaccinate an unhealthy animal, vaccines take 2-4 weeks to reach protection, vaccines should be tailored to fit needs of the animals, Vaccines have side effects, most first vaccines need boosters, timing of vaccines depend on type of protection needed
What does a fever do to a vaccine?
Eliminates the response and immunity
Examples of side effects
Soreness at the site, lethargy, fever and joint pain, abscesses at the site, swelling and hives, tumors at the site, can cause the disease
Are vaccines 100% effective?
NO!
How are vaccines stored?
Refrigerated, unexposed to heat and sunlight, uncombined
Most common routes of vaccination.
SQ and IM
What route is used for vaccinating large groups?
Aerosolized
How do you vaccinate fish?
Through water
When is the first vaccine able to be given?
8 weeks of age
What are the two core vaccines?
Distemper and rabies
Symptoms of distemper?
Fever, cough, nasal discharge, encephalitis, neurological signs, hypercaritonic foot pad (rough foot pads), cns effects during later stages
How do you treat distemper?
Viral infection—Can only treat symptoms with nutrition, antibiotics, fluids
Describe process of vaccinating for distemper
Given at eight weeks. 2-3 series 3-4 weeks apart