Immunology - German Flashcards
What are the 4 classes of pathogens
- bacteria
- Virus
- fungi
- parasites
What is the role of the immune system?
- Kill pathogens
- Control disease
- repair tissue damage
- organ development
- maintain organ integrity
What physical barriers does the body have to protect itself?
Skin & Mucosal surfaces
ALSO
Endogenous antimicrobial properties
What are the 3 common immune effector mechanisms?
Phagocytosis
Granule release
Trageted cell death
What are a few KEY differences between Innate Immunity and Adaptive immunity?
Innate:
- Rapid response (hours)
- Fixed response
- Limited pathogen specificity
- Consistent response
Adaptive: -Slow response (days- weeks) - Flexible response - Very selective pathogen specificity - Retains MEMORY
A fixed response is an example of adaptive/innate immunity
Innate
A rapid response is related to adaptive/innate immunity
Innate
- Epithelial barriers
- Phagocytes
- Dendritic cells
- Complement
Are all examples of what type of immunity
Innate
- B lymphocytes
- Antibodies
- T lymphocytes
- Effector T cells
Are all examples of what type of immunity
Adaptive
Phagocytosis is an example of (direct/indirect) interaction
Direct
T cell mediated killing is an example of (direct/indirect) interaction
Direct
Cytokines are an example of (direct/indirect) interaction
Indirect
Molocules that attract immune cells to a region of the body are known as…..?
Chemokines (indirect)
What is the most common type of white blood cell in the body
Neutrophil
Neutrophil, basophil, Eosonophil are all examples of innate/adaptive immunity?
Innate
Which innate immune cell is known as the “1st responder”
Neutrophil
How do macrophages kill and what do they promote?
Kill by phagocytosis
Promote - inflammation
What is the difference between humoral and cellular immunity responses
Humoral - Antibody mediated
Cellular - Cell-cell interactions
Antibodies are an example of ………….. response
Humoral (Also adaptive)
What are the 2 types of T cells and what do they do?
(CD8) Cytotoxic cells - kill altered self cells
(CD4) Helper T cells - support other immune functions
Bone marrow and Thymus are an example of (primary/secondary) Lymphoid tissue
Primary
Where doe immune cells develop
In primary lymphoid organs
T or F:
The spleen, lymphoid system and mucosa associated tissue are an example of primary lymphoid organs
FALSE
List the basic process of pathogen resolution
- pathogen infiltration
- Immune cells respons
- Inflammatory response
- INNATE pathogen targeting
- Pathogenic antigens presented in the lymph nodes
- ADAPTIVE immunity intiated
- Ongoing Immune response
- Pathogen destroyed or sequestered
- Memory cells formed
