Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

2 Opthalmology > Immunology > Flashcards

Immunology Flashcards

1
Q

what immune property do tears have?

A

they wipe away debris from the outer layer of the eye

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

are commensal bacteria an innate or adaptive

A

innate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is chemotaxis?

A

chemical signals drawing in enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

5 immune mediators involved in the in the immediate innate response?

A 
anti microbial proteins
complement
mast cells
macrophages
inflammation
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

2 immune mediators involved in the early immune response?

A

recruitment/activation of phagocytes

inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what timeframe does the immediate immune response start at?

A

0-4hrs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what timeframe does the early immune response start at?

A

4-96hrs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what time does the adaptive immune response start at?

A

96hrs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

is the adaptive or innate immune system responsible for memory?

A

adaptive immune system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is the main problem with the physical barrier of the eye?

A

there is none so it is exposed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

how does the eye combat bacteria non chemically?

A

blink reflex

mucus layer is anti-adhesive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what does lysozyme do?

A

destroys bacterial cell wall

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what do tears contain to make them anti-inflammatory?

A

lipids

angiogenin in tear film

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what does secretory IgA do in the eye?

A

prevents attachment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what interleukins are present in the eye?

A

IL-6, IL-8

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what immune cells are present in the eye?

A

neutrophils
macrophages
mast cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

how do neutrophils get to the eye?

A

chemotaxis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what immune cells trigger the adaptive immune system?

A

macrophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

name the antigen presenting cells of the body

A

dendritic cells
B cells
macrophages

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

name the effector cells of the body?

A

cd4 t cells
cd8 t cells
b cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

principle antigen presenting cell of the external eye?

A

langerhans cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

which type of MHC cell is present in langerhans cells?

A

class 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

where in the eye are langerhans cells most abundant?

A

limbus

24
Q

where in the eye are langerhans cells least abundant?

A

cornea (central 1/3 in particular)

25
Q

only part of the eye with lymphatic drainage?

A

conjunctiva

26
Q

main lymphoid tissue present in the eye

A

MALT (mucosa associated lymphoid tissue)

27
Q

what cells are contained within the MALT of the eye?

A

macrophages
langerhans cells
mast cells

28
Q

what 2 types of cell does the lacrimal gland have more of compared to the conjunctiva

A

plasma cells

CD8 T cells

29
Q

what kind of cell are langerhans cells?

A

macrophages

30
Q

define immune privilege

A

a structure that is able to tolerate the introduction of antigens without eliciting an immune response from the rest of the body

31
Q

what structures are said to have immune privilege

A

placenta
eyes
testes

32
Q

what type of MHC molecules does the cornea express if any?

A

MHC class 1

33
Q

what does ACAID stand for?

A

anterior chamber associated deviation

34
Q

what is ACAID?

A

placement of an antigen into the eye to make the eye tolerant to it

35
Q

rare, bilateral granulomatous uveitis?

A

sympathetic opthalmia

36
Q

cause of sympathetic opthalmia?

A

trauma

surgery in 1 eye

37
Q

is 1 or both eyes affected in sympathetic opthalmia?

A

2 but only 1 eye is actually injured, they both appear the same

38
Q

medical name for dry eyes

A

keratoconjunctivitis sicca

39
Q

cause of lens uveitis?

A

damage to lens capsule

immature lens

40
Q

what is the constant region of an Ab called?

A

Fc

41
Q

what is the antibody specific region of an Ab called?

A

Fab

42
Q

what kind of hypersensitivity is acute allergic conjunctivits?

A

type 1

43
Q

what is chemosis?

A

oedema of the conjunctiva

44
Q

2 ways in which cells are killed in type 2 hypersensitivity

A

macrophages/NK cells

complement

45
Q

type of hypersensitivity involved in ocular cicatricial pemphigoid?

A

2

46
Q

clinical presentation of ocular cicatricial pemphigoid?

A

blistering and scarring of conjunctiva
hazy cornea
vascularisation

47
Q

treatment for ocular cicatricial pemphigoid?

A

steroids

immune modulators

48
Q

what does chemosis look like?

A

jelly

49
Q

outer layer of the cornea melting with inner layer bulging forward?

A

autoimmune corneal melting

50
Q

what kind of hypersensitivity reaction is autoimmune corneal melting

A

3

51
Q

what type of hypersensitivity undergoes clonal expansion

A

4

52
Q

what hypersensitivity would tissue/graft rejection come under?

A

4

53
Q

what could you see on examination of the cornea to suggest rejection?

A

vascularisation of cornea

54
Q

treatment of most autoimmune eye conditions?

A

steroids

55
Q

steroid ocular side effects?

A

cataracts

steroid induced glaucoma

2 Opthalmology (13 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions