Immunology 3 Flashcards
What is active immunity?
When the host responds to a specific antigen
What is passive immunity?
Adoptive transfer of antibodies into the host
What are naive lymphocytes?
They are lymphocytes that have not yet encountered a particular antigen
What’s an example of passive immunity?
Transferral of maternal antibodies to a foetus.
What is “natural active”
The hosts own response to an infection
What is “artificial active”
The hosts response to ingested antigens
What is “natural passive”
Transferral of antibodies across the placenta
What is “artificial passive”
Introduction of antibodies from a separate host, e.g. when to treat ebola
Where are B cells produced?
Bone marrow
What is meant by B cells “selecting gene sequences”?
This means only a single B cell will translate the BCR from that gene
How is the B cell activated in 2 ways?
- T cell dependent
- T cell independent
What isn’t enough to activate a B cell on its own?
Clustering of BCR’s
How does T cell activation occur?
The T cell recognises a certain BCR on a BCR cluster and binds to it
What is the first antigen produced by any B cell?
IgM
What is T cell independent activation?
When the B cell recognises self antigens and activates
