Immunology 2 Flashcards

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1
Q

What are the 3 functions of the lymph system?

A
  • Drain tissue fluid
  • Absorption and transport of FA
  • Immunity
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2
Q

Why does lymph only travel one way?

A

The lymphatic vessels have valves

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3
Q

What are the two main ducts of the lymphatic system?

A
  • Thoracic duct

- Right duct

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4
Q

Where does the lymph that drains into the thoracic duct come from?

A

The left upper and lower, and the right lower quarters of the body

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5
Q

Where does the lymph that drains into the right duct come from?

A

The upper right quarter

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6
Q

What is the function of the 2 primary lymphoid organs?

A

Haematopoiesis of wbc

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7
Q

What are the 2 primary lymphoid organs?

A
  • Thymus (T cell education)

- Bone marrow

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8
Q

What is the function if the secondary lymphoid organs?

A

Lymphocyte activation

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9
Q

What is the primary function of the spleen?

A

Blood filtration

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10
Q

What is contained in the red and white pulp of the spleen respectively?

A
  • RBC’s

- WBC’s

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11
Q

“Lymphocytes like to go on pub crawls” what does this mean?

A
  • They travel from lymph node to lymph node
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12
Q

What are peyers patches?

A

Areas in your gut that sample the stuff in the gut

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13
Q

What do peyers patches hope to catch?

A

Antigens

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14
Q

Where do peyers patches transport the antigens?

A

The lymph system, it then interacts with lymph nodes

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15
Q

What do dendritic cells do when they come into contact with an antigen?

A
  • Phagocytose it

- Present it on their surface as MHC2

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16
Q

What do T lymphocytes have on their surface that can interact with MHC?

A

T cell receptors

17
Q

What T cells are formed when viral protein is found on MHC 1?

A

CD8 (cytotoxic)

18
Q

What T cells are formed when viral protein is found on MHC 2?

A

CD4

19
Q

What is positive selection with regards to T cells?

A

They’re shown a range of antigens on cells and if they recognise none they will be killed

20
Q

What is negative selection with regards to T cells

A

They’re shown our proteins and if they bind they are killed