Immunology 2

Question 1

What are the 3 blood cell lineages?

Answer 1

Erythroids (red blood cells), myeloid, lymphoid

Question 2

What are examples of myeloid cells?

Answer 2

Granulocytes, mast cells, platelets and dendritic cells

Question 3

What are examples lymphoid cells?

Answer 3

B and T cells (adaptive immune cells)

Question 4

This cell makes up 75% of all leukocytes. It is highly phagocytic and numbers in blood increase during infection (key word BLOOD)

Answer 4

Neutrophils

Question 5

These cells line up mucosal surfaces (not found in blood but rather TISSUE) they release granules that attract white blood cells to areas of tissue damage

Answer 5

Mast cells

Question 6

These cells are present in blood and are not really phagocytic. But once they move out of the blood and into the tissue, they develop into macrophages which are highly phagocytic

Answer 6

Monocytes

Question 7

These cells are present in tissue and are highly phagocytic. They can either stay in tissue or move through tissues (migratory)
- they also show information about pathogenic microbes to T cells (which links adaptive and innate immunity)

Answer 7

Macrophages

Question 8

These cells are found in low numbers in the blood. They are phagocytic and highly important in triggering adaptive immune responses due to structures known as dendrites.

Answer 8

Dendritic cells

Question 9

How do cells of the immune system move around the body?

Answer 9

Through lymph and blood

Question 10

How do innate cells recognise patterns?

Answer 10

PAMPS - Pathogen-Associated Molecular Pattern