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PBL > IMMUNO > Flashcards

IMMUNO Flashcards

1
Q

Secreted by: maacrophages and T cells

A

TNF

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2
Q

Secreted by Marcrophages endothelial cells

A

IL-1

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3
Q

Secreted by macrophages, dendritic cells, endothelial cells, T lymphocytes, fibroblast, platelets

A

Chemokine

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4
Q

Secreted by dendritic cells and macrophages

A

IL-12

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5
Q

secreted by NK cells and T lymphocytes

A

IFN y

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6
Q

IFN-a is secreted by

A

dendritic cells and macrophages

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7
Q

IFN-B is secreted by

A

fibroblasts

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8
Q

secreted by dendritic cells macrophages and t cells

A

IL-10

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9
Q

Secreted by macrophages, endothelial cells, T cells

A

IL-6

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10
Q

IL-15 secreted by

A

macrophages

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11
Q

IL-18 secreted by

A

macrophages

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12
Q

Inhibits inflammation
differentiation of Th17
regulatory T cells

A

TGF-B

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13
Q

NK and T cell proliferation

A

IL15

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14
Q

Stimulates liver to synthesis acute phase proteins

B cells: proliferation of Ab producing cells

A

IL6

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15
Q

Inhibits IL-12 production and reduced expression of costimulator and class II MHC

A

IL10

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16
Q

Activation of macrophages

A

IFN-y

17
Q

stimulates leukocytes: increased integrin affinity, chemotaxis, activation

A

Chemokines

18
Q

Endothelial cells: activation
Fever
Liver: acute phase proteins
TH17 differentiation

A

IL-1

19
Q 
Muscle, fat: catabolism
apoptosis of cells
endothelial activation
neutrophil activation
syn of acute phase proteins
A

TNF

20
Q

C3a of complement stimulates

A

inflammation

21
Q

C3b of complemnet stims

A

opsonization and pagocytosis

22
Q

C5a stimulates

A

inflammation

23
Q

Plasma TLR

A

1,2,4,5,6

24
Q

Endosome TLR

A

3789

25
Q

TLR 1 and 2 and 6

A

Bacterial lipopeptides

26
Q

TLR-2

A

bacterial peptidoglycans

27
Q

TLR-4

A

LRS

28
Q

TLR-5

A

bacterial flagellin

PBL (19 decks)

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