GI PHYS Flashcards
S Cells
duodenum, jejunum, ileum
secrete secretin
stimulated by acid and fat
Secretin
STIMULATES: pepsin secretion, pancreatic bicarb, biliary bicarb, growth of exocrine pancreas
INHIBITS: gastric acid secretion
G cells
antrum, duodenum, jejunum
secretes gastrin
stimulated by protein, distention, nerve
inhibited by acid
Gastrin
STIMULATES: gastric acid secretion, mucosal growth
I cells
Duodenum, jejunum, ileum
secretes Cholescystokinin
stimulated by Protein, fat and acid
CCK
STIMULATES: pancreatic enzyme secretion, pancreatic bicarb secreion, gallbladder contraction, growth of exocrine pancrease
INHIBITS: gastric EMPTYING
K cells
Duodenum and jejunum secretes GLIP (glucose dependent insulin ionotropic peptide) stimulated by: Protein Fat Carb
GLIP
STIMULATES: insulin release
INHIBITS: gastric acid secretion
M cells
duodenum and jejunum
secretes Motilin
stim by fat acid nerve
Motilin
STIMULATES: gastric motility, intestinal motility
gastrocolic reflex
signals from stomach causes evacuation of colon
enterogastric reflex
signal from colon and SI inhibit stomach motility and stomach secretion
coloileal reflex
reflex from colon inhibits emptying of ileal content into colon
receptive relaxation
gut relaxes several centimeters towards anus from distention
What 3 chemicals directly stimulate parietal cells to secrete acid and act in a multiamplificative way
Acetylcholine, histamine, gastrin