BIOCHEM 35 Flashcards

1
Q

PGI, PGE, PGD decrease

A

platelet aggregation, Leukocyte aggregation

IL1, IL2 T-cell proliferation

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2
Q

PGI, E, D increases

A

vasofilation, cAMP

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3
Q

PGFa increases

A

vasoconstriction, bronchoconstriction, SM constraction

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4
Q

Primary function of COX-1

A

platelet aggregation, STOMACH CYTOPROTECTION

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5
Q

primary function of COX- 2

A

Inflammation, hyperalgesia

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6
Q

LTB4

A

increases vascular permiability, T cell proliferation, leukocyte aggregation, INF-y, IL1, IL2

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7
Q

LTC4 and LTD4

A

increase bronchoconstriction, vascular permeability, INF-y

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