immune system charts and difficult stuff

Question 1

3 APC cells

Answer 1

macrophages, dendritic cells, B cells

Question 2

B cell receptors

Answer 2

recognize soluble macromolecules and small chemicals

Question 3

T cell receptors

Answer 3

recognized processed antigen fragments presented by HLA /MHC on APC

Question 4

what do helper t cells make

Answer 4

cytokines: IL 2 and IF gamma

Question 5

tell me about helper t cells

Answer 5

CD 4
recognize class 2 MHC
make cytokines IL2 and IF gamma

Question 6

tell me about cytotoxic t cells

Answer 6

CD 8
recognize class 1 MHC
kill virally infected and tumor cells

Question 7

what are NK cells enhanced by

Answer 7

antibodies and helper t cells

Question 8

what are the specific APC

Answer 8

B cells

Question 9

where do memory cells reside

Answer 9

bone marrow or lymph nodes and go to the site of infection when needed

Question 10

what is IL 2 stimulated by

Answer 10

IL 1, IL6 and TNF

Question 11

what does IL 1, IL6 and TNF respond to

Answer 11

fever, inflammation, infection, and injury

Question 12

what does IL 2 target

Answer 12

helper t cells, cytotoxic t cells, NK cells, and B cells

Question 13

what is the function of IL 2

Answer 13

stimulate proliferation and promote conversion of plasma cells

Question 14

what do plasma cells arise from

Answer 14

b cells

Question 15

what does IF type 1 do (alpha and beta)

Answer 15

stimulate cells to make antiviral proteins and prevent viral replication in host

Question 16

where is IF type 2 (gamma) secreted from

Answer 16

NK cells and helper t cells

Question 17

what does IF type 2 stimulate

Answer 17

proliferation and secretion of cytotoxic compounds

Question 18

where are cytokines secreted? what do they target?

Answer 18

secreted from damaged cells and target neutrophils and WBC

Question 19

function of cytokines?

Answer 19

assist in injury and inflammation; facilitate accumulation of WBC at site of injury and inflammation

Question 20

where is CSFS secreted? what do they target?

Answer 20

secreted from macrophages that target bone marrow

Question 21

what does CSF do

Answer 21

stimulate proliferation of neutrophils and monocytes

Question 22

3 functions of helper t cells?

Answer 22

1. secrete IL
2. convert b cells to plasma cells
3. keep NK cells, macrophages, cytotoxic t cells, and helper t cells active

Question 23

what is delayed hypersensitivity mediated by?

Answer 23

helper t cells and macrophages

Question 24

what is immune complex hypersensitivity mediated by?

Answer 24

antigen-antibody complexes deposited in tissue

Question 25

what is cytotoxic hypersensitivity mediated by?

Answer 25

antibodies that lead to damage of cells such as in hemolytic diseases of newborns

Question 26

what is immediate hypersensitivity mediated by?

Answer 26

IgE, mast cells, eosinophils

Question 27

ex of delayed hypersensitivity?

Answer 27

poison oak/ivy, TB test

Question 28

ex of immune complex hypersensitivity?

Answer 28

lupus

Question 29

ex of cytotoxic hypersensitivity?

Answer 29

Rx factor

Question 30

ex of immediate hypersensitivity?

Answer 30

inhale/food allergy