immune system and viruses Flashcards
immune responses
- Nonspecific - barriers (i.e. skin), inflammatory response\
- Specific - cell + antibody mediated immunity
first line of defense
Nonspecific barriers (i.e. mucus/bacteria in mouth/macrophages)
Second line of defense
Second line of defense - Nonspecific inflammatory response
- If pathogen gets into the body - histamines released from injured body cells that cause area to swell
- Capillaries will dilate brining more blood with white blood cells (phagocytes) to destroy pathogen
Third Line of Defense
Third Line of Defense - Specific immune response
- Triggered by antigens
- Antigens - any foreign substance that can stimulate an immune response (marker proteins on bacteria/virus/parasites)
- Antibodies - large Y-shaped proteins used to identify + neutralize foreign objects
- Immune system responds to antigens by increasing number of cells that can attach to invaders directly or that produce antibodies to tag them for destruction
- Tagged pathogens will signal T and B cells to destroy and get rid of it
allergies
Allergies - result from immune cells that over-respond to non-pathogenic substances
- Allergens (pollen/dust/etc.) can trigger inflammatory responses and release histamines which cause sneezing/itching/etc.
virus overview
- Nonliving
- Specific to organism they attack and will use cell organelles to carry out their job (hijacks cell)
- Bacteriophage - virus that infects a bacteria
- Structure
- Non-cellular infectious agent
- Contains a protein coat called the capsid
- Has genetic material (DNA/RNA)
immune system overview
Body’s defense against disease causing agents, malfunctioning cells, and foreign particles
- Innate immunity - effective from the time you are born
- Acquired immunity -developed over time from exposure to pathogens and vaccines
virus reproduction
- Attachment - virus attaches to receptors on host cell
- Penetration - virus particle/genetic material crosses cell membrane of a host cell and enters cytoplasm
- Replication + Synthesis - viral DNA/RNA replicates and makes new viral parts
- Assembly - new viruses are made inside host cell
- Release - particles are released from host cell and can cause cell death
lytic cycle
Steps of attachment occur quickly until cell bursts open and new viruses are spread to surrounding cells