Immune disorders Flashcards
1
Q
What is SCID
A
Loss of T and B cells (Individuals often don’t survive long due to lack of immune system.
2
Q
Describe Rheumatoid arthritis
A
Autoimmune disease - hyper active immune system that attacks own cells. Particularly synovial joints, causing chronic inflammation.
3
Q
Why do allergic reactions occur
A
Immune system (APC) confuses Allergens as antigens and launches a response
4
Q
Describe type 1 hypersensitivity
A
B cells produces antibody (IgE), which binds to mast cells through FC receptors
When exposed to allergen again mast cells degranulate releasing cytotoxins
5
Q
What antibody is produced most during type 1 allergic reaction
A
IgE - large, monomeric.
6
Q
What do mast cells release
A
Histamine - causes symptoms of reaction and occurs immediately
