IDA

Question 1

Hematological findings

Answer 1

less Hb
less Hct
less RBC count
MCV:<76 fl
MCH:< 26pg
Less reticulocyte
TLC:n
Platelets:inc/n

Question 2

peripheral smear,RBC

Answer 2

Hypochromic microcytic anaemia
anisopoikilocytosis
shape:elliptocytes,pencil shape,few target cells
immature form:nucleated
reticulocytes not seen
no RBC inclusion
no rouleaux formation

Question 3

peripheral smear,others

Answer 3

wbc:n
platelets:n/inc

Question 4

BM findings

Answer 4

erythropoiesis:erytjroid hyperplasia

smaller RBC percursors :micronormoblast

granulopoiesis n megakaryopoeisis:N

marrow iron stores( Perl’s Prussion blue stain); absent

Question 5

biochem :serum iron study

Answer 5

dec serum Fe
dec ferritin
dec hepcidin (dec fe store inhibit synthesis)
inc Total Iron Binding Capacity(TIBC)

Question 6

INVESTIGATION FOR UNDERLYING CAUSE

Answer 6

Stool RE:occult blood,hook worm ova
urine re: red cell casts,rbc
radiology: CXR,Barium studies
endocopic examination: Gi lesion
LFT: liver cirrhosis,esophageal varices

Question 7

clinical features

Answer 7

pallor of mucosa
fatigue
breathlessness
poor appetite
missed menstruation
anaemic heart failure

Question 8

epithelial tissue change

Answer 8

• Fe req for intergrity of normal epithelial tissue
  nail:lusterless,koilonychia
  tongue:atrophic glossitis
  mouth:angular cheilosis, angular stomatitis
  hair:thin,lusterless,brittle

Question 9

paterson kelly syndrome(Plummer Vinson’s Syndrome0

Answer 9

upper esophagial web(premalignant)
IDA
glossitis n angular stomatitis

Question 10

children

Answer 10

pallor,anorexia,irritability,pica,periodic movment of limbs during sleep

Question 11

1st sign of response to treatment

Answer 11

inc reticulocyte