IBR Flashcards
Bovine Herpes Virus 1 causes 3 clinical manifestation
infectious bovine rhinotracheitis (IBR)
infectious pustular vulvovaginitis (IPV)
Infectious pustular balanoposthitis (IPB)
What is the most common clinical manifestation of disease that occurs during primary infection with BoHV-1
IBR
How is BoHV-1 most commonly transmitted
Direct contact/Respiratory secretions
Outline stages of IBR disease
Primary infection- Sheds virus
Latent infection
Secondary infection that can be induced by stress
What stage of disease does animal show clinical sign
Primary stage
C/S of IBR
Respiratory signs
Dull
Reduced milk yield
Pyrexia
Conjuctivitis/Nasal ocular discharge
Rapid and loud breathing with cough
Abortion
Will latent infected animal show antibody titre
Yes
Dx of IBR
Ocular conjunctival swab
PCR
Increase in antibody titre
Tx of IBR
Vaccination
NSAIDS
AB for secondary infection
What are vaccines licensed to do in IBR
- Reduce severity of C/S
- Reduce shedding during primary infection
- Reduce the likelihood and duration of shedding from reactivation
What does vaccines NOT do in IBR
Do not prevent reactivation/latent infections
What vaccines do I choose (Live/Inactivated)
Live primarily chosen. Offer faster protection against clinical signs if given intranasally
What is the key difference in conventional vaccine and marker vaccine in terms of antibody type they will produce
Marker vaccine will not stimulate production of Glycoprotein E
Both vaccines stimulate GpB
Why using antibody titre to detect gpE and gpB could be challenging in a vaccinated cow
Both gp will be seen in vaccinated animal with conventional vaccine without an infection
Most common route of a IBR outbreak
New introduction to Naive herd