Hypotension triggers

Question 1

hand clenching, leg crossing and leg muscle flexing used to treat what

Answer 1

physical maneuvers for tx of orthostasis (orthostatic hypotension)

Question 2

increases peripheral vascular resistance, therefore increasing BP

Answer 2

midodrine

Question 3

does not cross blood brain barrier

Answer 3

midodrine

Question 4

does not generally present with fatigue, nausea, or confusion

Answer 4

orthostatic hypotension

also POTS

Question 5

is there a drop in BP with POTS

Answer 5

NOOOOOOO

Question 6

MC in young female pts

Answer 6

POTS

Question 7

caused by neurodegenerative diseases such as parkinsons

Answer 7

orthostatic hypotension

Question 8

caused by neuropathies as result of DM, B12 deficiency, amyloidosis, sarcoidosis, or Lyme disease

Answer 8

orthostatic hypotension

Question 9

SE: edema, supine HTN

Answer 9

fludrocortisone

also:
hypokalemia

Question 10

SE: hypokalemia

Answer 10

fludrocortisone

also:
edema
supine HTN

Question 11

must be dosed TID due to short half life

Answer 11

midodrine

Question 12

hypotension leading to poor perfusion and end-organ damage

Answer 12

cardiogenic shock

Question 13

elevated troponin or CX-MB

Answer 13

recent/acute MI indication

Question 14

what is the criteria for orthostatic hypotension

Answer 14

A 20 mmHg fall in SBP
OR
A 10 mmHg fall in DBP

after standing from a lying position

Question 15

elevation in serum Cr, AST, and ALT

Answer 15

indications of hepatic and renal hypoperfusion

Question 16

initial evaluation includes:
CBC
CMP
EKG
TFTs

Answer 16

POTS

Question 17

start at .1mg and titrate up every week until you get to .3mg

Answer 17

fludrocortisone

Question 18

increases sodium reabsorption and potassium excretion in distal tubules

Answer 18

fludrocortisone

Question 19

mineralcorticoid with high glucocorticoid activity

Answer 19

fludrocortisone

Question 20

SE: piloerection, GI effects, urinary retention or urgency

Answer 20

midodrine

also see:
supine HTN
paresthesias
pruritus

Question 21

SE: supine HTN, paresthesias, pruritus

Answer 21

midodrine

Question 22

caused by impairment of autonomic reflexes or volume depletion

Answer 22

orthostatic hypotension

Question 23

alpha 1 selective andrengeric agonist

Answer 23

midodrine

Question 24

2.5 mg TID then titrae to 10 mg TID for desired response

Answer 24

midodrine

Question 25

BB, SSRI, SNRI, Midodrine, fludrocortisone

Answer 25

POTS pharm tx

Question 26

what medication classess can cause orthostatic hypotension

Answer 26

Question 27

coagulation abnormalities and anion gap acidosis suggests what

Answer 27

hepatic congestion or hepatic hypoperfusion

also see:
elevated serum lactate

Question 28

elevated serum lactate indicative of what

Answer 28

hepatic congestion or hepatic hypoperfusion

also see:
coagulation abnormalities
anion gap acidosis

Question 29

lifestyle changes includes aerobic exercise for lower extremities

Answer 29

POTS

Question 30

after starting this medication, youll want to get a BMP

Answer 30

fludrocortisone d/t hypokalemia

Question 31

what is the possible etiology of POTS

Answer 31

Distal denervation
Hypovolemia
Venous dysfunction
Cardiovascular deconditioning
Baroreflex abnormalities
Increased sympathetic activity
Genetic abnormalities

BIG D CHV