Hyperthyroidism & HYPOTHYROIDISM Flashcards
What is the most common type of hyperthyroidism
The autoimmune disease called Graves’ disease
What are signs and symptoms of hyperthyroidism
Hyper metabolism( ^ appetite with weight loss)
Heat intolerance ( ^ sweating is the hallmark sign)
Widening pulse pressure
Systolic HTN
tachycardia ( 90-160), atrial fibrillation, dysrhythmias, palpitations
Angina, CHF ( decompensation leads to HF)
Increased peristalsis ( diarrhea), hyperactive bowel sounds
Nervousness, restlessness, insomnia
Fine tremors ( hyperreflexia)
Mood swings, decrease in concentration
Hair loss, smooth, warm skin, facial flushing
Amenorrhea
Libido increase then decreases as condition progresses
Graves’ disease is most common in who
Females ages 20-40
What are signs and symptoms of Graves’ disease
Signs of hyperthyroidism AND enlarged thyroid gland ( goiter)
Proprosis ( forward displacement of eyes causing blurred vision, diplopia, lacrimation, and photophobia.)
Exophthalmos
Changes in menstration
What is exophthalmos
Forward protrusion of the eyes causing corneal dryness, irritation, ulceration ; it is a classic sign of Graves’ disease
The eyelids won’t close, give artificial tears to control dryness along with cool moist compresses, wear tinted glasses or eye shields to protect the eyes.
Elevate the bed 45 degrees to keep pressure off optic nerve.
What is toxic multinodular goiter
Nodules in thyroid tissue that secrete excessive thyroid hormone.
Is usually appears in woman 60-70 yrs of age, who had a goiter for a number of years
What is thyroid crisis
AKA thyroid storm or thyroidtoxicosis
It is a medical emergency, has a high mortality rate
Occurs with untreated hyperthyroidism
What can bring about thyroid crisis
Digoxin toxicity
Increase in stress
Extreme state of hyperthyroidism ( rare now)
Occurs with untreated hyperthyroidism or hyperthyroid person with stressors such as infection, trauma, manipulation of thyroid during surgery.
Why is thyroid crisis dangerous
It is a life threatening condition with excess metabolic symptoms such as temp of 102-106, HTN, tachycardia, and agitation advancing to seizures, psychosis, delirium.
What is treatment of thyroid crisis
Reducing thyroid secretion
Stabilizing cardiovascular system
Managing respiratory distress
What are diagnostic tests for hyperthyroidism
Serum thyroid antibodies ( TA)..... Antibodies in Graves' disease TSH test ( from pituitary) T3 & T4 RAI uptake test Thyroid suppression test
In diagnosing hyperthyroidism what will the clients TSH levels look like
They will be suppressed with primary hyperthyroidism
In diagnosing hyperthyroidism, what will the clients T3 &and ; T4 look like
They will be elevated
What is the RAI uptake test
Oral or intravenous dose of radioactive iodine 131 is given, then a thyroid scan after 24 hours, the size and shape of the gland is revealed. Uptake is increased with Graves’ disease.
What is thyroid suppression test
RAI and T4 are measured then remeasured after client takes thyroid hormone
( no suppression is noted with hyperthyroid
What is hyperthyroidism
Excessive delivery of thyroid hormone to peripheral tissues
It can be caused by excessive intake of medications ( exogenous) or neoplasms ( toxic multinodular goiter)
What are medications for hyperthyroidism
Antithyroid medications that block the synthesis of thyroid hormones such as; propylthiouracil (PTU) &; methimazole ( tapazole) more toxic than PTU
BETA BLOCKERS that controls symptoms such as tachycardia, tremor etc such as Propanolol ( Inderal) & atenolol ( temormin) for those with cardiac or asthma problems.
What is used to treat hyperthyroidism
Radioactive iodine therapy
The process includes iodine being taken up by the thyroid I which it concentrates in the thyroid gland and destroys cells, thus less hormone is produced
How is radioactive iodine therapy administered
Orally
Results occur in 6-8 weeks
DO NOT GIVE TO PREGNANT WOMAN
The client is often HYPOTHYROID after treatment
What is surgery for hyperthyroidism
Subtotal thyroidectomy: only part of the thyroid is removed
Total thyroidectomy to treat cancer of thyroid( client will need lifelong thyroid replacement).
What must be done prior to surgery for hyperthyroidism
Get client into a euthyroid state
Give potassium iodine prior to surgery to decrease size and vascular its of thyroid
What are post op concerns for surgery for hyperthyroidism
Airway: maintain airway; oxygen, suction, have tracheostomy set available.
Hemmorage: check neck dressing including posteriorly: it can compress the trachea.
Hypocalcemia: parathyroid glands may be removed or damaged, resulting in low calcium
For hypocalcemia what should be on hand
Calcium chloride or calcium gluconate
What is hypothyroidism
The thyroid gland produces insufficient amounts of thyroid hormone
What is myxedema
It is related to hyperthyroidism
It the the characteristic accumulation of non pitting edema in connective tissues throughout the body, water retention in mucoprotien deposits in interstitial spaces
More common in females ages 30-60.
What is the pathophysiology of hypothyroidism
Primary is more common There is a defect in the thyroid gland Congenital defects Post treatment of hyperthyroidism is a cause Iodine deficiency is a cause