Altered Immunity HANDOUT Flashcards

1
Q

What are the 3 altered immunities that can occur?

A
  1. Overreaction: hypersensitivity, as with allergic reactions
  2. Incompetency: immune deficiency or malignancy as with AIDS
  3. Autoimmune: loss of ability to recognize self
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2
Q

What are helper T cells

A

Carries CD4 antigen

Initiates immune response

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3
Q

What are suppressor T cells

A

Carries CD8 antigen

Stops immune response

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4
Q

T F

Immune function declines with age

A

True

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5
Q

What are cytotoxic Killer T Cells

A

Carries CD8 antigen
Attacks malignant cells
Responsible for transplanted organ rejection and grafted tissues.

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6
Q

Antihistamines

A

Blocks histamine receptors
Relieves symptoms of urticaria and angioedema
Diphenhydramine can be given parenterally or orally.

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7
Q

Epinephrine

A

Immediate treatment for anaphylaxis
Relieves the vasodilation and bronchoconstriction
Given SC or IV
Bee sting kit carries by ppl with known serious allergies

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8
Q

What does a healthy immune system do?

A

It identifies antigens and effectively destroys or removes them.

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9
Q

IgG

A

Most abundant
Activated complement system

Phagocytosis

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10
Q

IgA

A

Protects against rep, GI,GU Infections

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11
Q

IgM

A

1st present in bacterial and viral infections

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12
Q

What are the 2 types of immune responses

A

Antibody- mediated
( B Lymphocytes: ACQUIRED IMMUNITY)

Cell mediated
( T Lymphocytes attack antigens directly and activate B cells

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13
Q

What is cromolyn ( Intal)

A

Blocked histamine release

Given via inhaler or nasal spray

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14
Q

What types of effects do glucocorticoids have

A

Both topical and systemic effects

Anti inflammation

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15
Q

What is plasmapheresis

A

A non. Medicational treatment that remove harmful components in plasma by passing blood through cell separator to remove immune complexes.

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16
Q

What is type 1 reaction

A

Most serious reaction ( anaphylaxis)

17
Q

What are signs and symptoms of type 1 reaction

A

Hives , swelling, dyspnea,

Anaphylactic shock

18
Q

What is prompt reversal of type 1 reaction

A

Parenteral epinephrine

19
Q

What is type 2 reaction

A

(IgG IgM)Hemolytic transfusion blood reaction (ABO, Rh)

Complement cascade is activated and destroys cells

20
Q

What is type 3 allergic reaction

A

IgG or IgM
Antibody- antigen immune complexes in circulation and block tissues such as reaction to toxic strep infection ,glomerulinephritis

21
Q

What is type 4 reaction

A

Delayed 24-48 hours
Such as in contact dermatitis; latex allergy,
Positive TB test)
ANTIGEN- LYMPHOCYTE REACTION

22
Q

What are the 2 types of immune responses

A

Antibody- mediated
( B Lymphocytes: ACQUIRED IMMUNITY)

Cell mediated
( T Lymphocytes attack antigens directly and activate B cells

23
Q

What is cromolyn ( Intal)

A

Blocked histamine release

Given via inhaler or nasal spray

24
Q

What types of effects do glucocorticoids have

A

Both topical and systemic effects

Anti inflammation

25
Q

What is plasmapheresis

A

A non. Medicational treatment that remove harmful components in plasma by passing blood through cell separator to remove immune complexes.

26
Q

What is type 1 reaction

A

Most serious reaction ( anaphylaxis)

27
Q

What are signs and symptoms of type 1 reaction

A

Hives , swelling, dyspnea,

Anaphylactic shock

28
Q

What is prompt reversal of type 1 reaction

A

Parenteral epinephrine

29
Q

What is type 2 reaction

A

(IgG IgM)Hemolytic transfusion blood reaction (ABO, Rh)

Complement cascade is activated and destroys cells

30
Q

What is type 3 allergic reaction

A

IgG or IgM
Antibody- antigen immune complexes in circulation and block tissues such as reaction to toxic strep infection ,glomerulinephritis

31
Q

What is type 4 reaction

A

Delayed 24-48 hours
Such as in contact dermatitis; latex allergy,
Positive TB test)