hypertension Flashcards

1
Q

what is hypertension?

A
  • high sustained arterial pressure

- 140/90

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2
Q

what is hypertension a risk factor for?

A
  • cerebral haemorrhage
  • atheroma
  • renal failure
  • sudden cardiac death
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3
Q

how is blood pressure calculated?

A
  • cardiac output x peripheral resistance
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4
Q

what is primary hypertension?

A
  • 90% of cases
  • salt intake -25% salt sensitive
  • renin - angiotensin system
  • sympathetic activity
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5
Q

what is salt sensitive hypertension?

A
  • increase in salt = increased BP

- in renal 27 hypertension is usually salt sensitive

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6
Q

what are the common causes of secondary hypertension?

A
  • renal disease
  • endocrine disease
  • aortic disease
  • renal artery stenosis
  • drug therapy
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7
Q

how do renal causes cause secondary hypertension?

A
  • eg renal artery stenosis
  • reduced renal blood flow
  • excess renin release
  • salt and water overload
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8
Q

how do endocrine causes cause secondary hypertension?

A
  • adrenal gland hyperfunction/tumours
  • conn’s syndrome - excess aldosterone
  • cushing syndrome - excess corticosteroid
  • phaecochromocytoma - excess noradrenaline
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9
Q

what can benign hypertension cause?

A

causes

  • left ventricular hypertrophy
  • congestive cardiac failure
  • increases atheroma
  • increases aneurysm rupture
  • renal disease
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10
Q

what is left ventricular hypertrophy?

A
  • increase LV load
  • poor perfusion
  • interstitial fibrosis
  • micro-infarcts
  • diastolic dysfunction
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11
Q

what are the consequences of benign hypertension?

A
  • every 10mmHg of diastolic pressure above 85 double risk of MI
  • every 8mmHg of diastolic pressure above 85 double risk of stroke
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12
Q

what is malignant hypertension?

A
  • diastolic pressure >130-140
  • can develop from either benign or secondary hypertension
  • needs urgent treatment
  • causes cerebral oedema
  • acute renal failure
  • acute heart failure
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13
Q

what is pregnancy associated hypertension?

A
  • increased maternal and fetal morbidity/mortality
  • ## pre-eclampsia = hypertension and proteinuria
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14
Q

when using ABPM to confirm diagnosis, what must you ensure?

A
  • at least two measurements per hour during the person’s usual waking ours
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15
Q

when using HBPM to confirm diagnosis, what must you ensure?

A
  • two consecutive seated measurements, 1 minute apart
  • BP is recorded twice a day for at least 4 days and preferably for 7 days
  • measurements on the first day as discarded - average value a=of all remaining is used
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16
Q

what is stage 1 hypertension?

A
  • clinic BP of 140/90mmHg or higher

- ABPM or HBPM daytime average of 150/95mmHg or higher

17
Q

what is stage 2 hypertension?

A
  • clinic BP or 160/100 or higher

- ABPM or HBPM daytime average of 150/95 or highrt

18
Q

what is stage 3 hypertension?

A
  • clinic BP is 180 or higher

- clinic diastole BP is 110 or higher

19
Q

what are you arrange for someone with hypertension?

A
  • test urine for presence of protein
  • take blood to measure glucose, electrolytes, creatine, estimated glomerular filtration rate and cholesterol
  • examine fundi for hypertensive retinotherapy
  • arrange a 12 lead ECG
20
Q

what are the risk factors of hypertension?

A
  • end organ damage eg left ventricular hypertrophy, creatine raised, albuminuria, retinopathy
  • age
21
Q

what BP should be aimed for?

A
  • 140/90 in under 80s

- 150/90 in above 80s

22
Q

what ABPM or HBPM BP should be aimed for?

A
  • below 135/85 in under 80s

- below 145/85 in above 80s

23
Q

what lifestyle choices should be suggested?

A
  • diet (no salt)
  • exercise
  • weight loss
  • alcohol consumption
  • smoking
24
Q

what are the treatment pathways for hypertension?

A
  1. under 55 = A
  2. above 55/african/carrbbean of any age = C
  3. A + C
  4. A + C + D
  5. resistant hypertension = A + C + D + consider further diuretic or alpha/beta blocker, consider seeing expert advice