hyperlipidaemia Flashcards
What are dangers of hyperlipidaemia?
It causes atherosclerosis (narrowing of blood vessel) and in turn:
coronary heart disease (angina,MI)
strokes and TIA
Peripheral arterial disease
What are cholesterol targets?
< or equal to TOTAL CHOLESTEROL 5mmol/L- healthy adults
< or equal to TOTAL CHOLESTEROL 4mmol/L- High risk adults
< or equal to LDL 3- healthy adults
< or equal to LDL 2 high risk adults
> 1HDL
<1.7mmol/L triglycerides
What drugs cause hyperlipidaemia
antipsychotics
immunosuppressants
corticosteroids
antiretrovirals (HIV drugs)
What condition causes hyperlipidaemia?
hypOthryoidism
Liver or kidney disease
DM
familial High cholesterol
Lifestyle: smoking, excessive alcohol consumption, obesity and poor fats diet.
What classes of drugs are used to regulate lipids?
Statins
Fibrates
Bile acid sequestrates
Nicotinic acid group
Lomitapide
Alirocumab