Fibrates Flashcards
1
Q
What is their mechanism of action?
A
Lowers blood triglyceride by reducing the livers production of VLDL and by speeding up the removal of triglycerides from the blood.
2
Q
What are it’s indications?
A
Severe hypertriglycerideaemia (>10mmol/L or in those who cannot tolerate a statin.
3
Q
Give examples of fibrates?
A
Bezafibrate
Fenofibrate
Ciprofibrate
Gemfibrozil- do not use with statins as high risk of myopathy (rhabdomyolysis)
4
Q
What are interactions?
A
Renal impaired
Statins
Myopathy
