Hydrocortisone

Question 1

Hydrocortisone - Drug Class/Presentation

Answer 1

Corticosteroid, 100mg vial

Question 2

Hydrocortisone - Pharmacology

Answer 2

Hydrocortisone is an adrenocortical steroid that produces an anti-inflammatory process. This inhibits the accumulation of inflammatory cells at inflammatory sites, phagacytosis, lysosomal enzyme release and synthesis and/or release of mediators of inflammation. Additionally, it prevents and surpasses cell mediated immune reactions

Question 3

Hydrocortisone - Metabolism

Answer 3

Hepatic

Question 4

Hydrocortisone - Onset, Duration, Half-life

Answer 4

Onset - 1-2 hours
Duration - 6-12 hours
Half-life - 6-8 hours

Question 5

Hydrocortisone - Indications

Answer 5

• Moderate OR severe asthma
• Acute exacerbation of COPD (with resp. distress)
• Severe allergic reaction OR anaphylaxis
• Symptomatic adrenal insufficiency

Question 6

Hydrocortisone - Contraindications

Answer 6

• KSAR or hypersensitivity to hydrocortisone

Question 7

Hydrocortisone - Precautions

Answer 7

• Hypertension

Question 8

Hydrocortisone - Side Effects

Answer 8

• Nil

Question 9

Hydrocortisone - Routes of Administration

Answer 9

• IM

- IV

Question 10

Hydrocortisone - Asthma, COPD, Allergy Adult Doses

Answer 10

• 200mg over 1 min

Question 11

Hydrocortisone - Symptomatic adrenal insufficiency Adult Doses

Answer 11

• 100mg over 1 min

Question 12

Hydrocortisone - Asthma, Allergy Paediatric Doses

Answer 12

• 5mg/kg over 1 min (not to exceed 100mg)

Question 13

Hydrocortisone - Symptomatic adrenal insufficiency Paediatric Doses

Answer 13

• 5mg/kg over 1 min (not to exceed 100mg)