Haloperidol

Question 1

Haloperidol - Drug Class/Presentation

Answer 1

Antipsychotic, 5mg/mL

Question 2

Haloperidol - Pharmacology

Answer 2

Haloperidol possesses a strong activity against delusions and hallucinations, most likely due to an effective dopaminergic receptor blockage in the mesocortex and the limbic system of the brain

Question 3

Haloperidol - Metabolism

Answer 3

By the liver with excretion in the urine, bile and faeces

Question 4

Haloperidol - Onset, Duration, Half-life

Answer 4

Onset - 5 mins (peak 20 mins)
Duration - 2-3 hours
Half-life - 20 hours

Question 5

Haloperidol - Indications

Answer 5

Acute psychosis (requiring pre-hospital intervention)

Question 6

Haloperidol - Contraindications

Answer 6

• KSAR or hypersensitivity to Haloperidol

- Parkinson’s disease

Question 7

Haloperidol - Precautions

Answer 7

• Patients who have taken alcohol or other drugs may develop severe hypotension
• ALOC
• Elderly debilitated patients
• History of dystonic reactions
• Neuroleptic Malignant Syndrom
• Tardive Dyskinesia

Question 8

Haloperidol - Side Effects

Answer 8

• Anxiety
• Euphoria
• Extrapyramidal reaction
• Hypotension
• Lethargy and drowsiness
• Respiratory depression

Question 9

Haloperidol - Routes of Administration

Answer 9

IM

Question 10

Haloperidol - Acute Psychosis Adult Doses

Answer 10

Greater than 50 - 5mg once

Less than 50 - 10mg once