HTN Prototypes Flashcards
hydrochlorothiazide therapeutic class:
diuretic
hydrochlorothiazide pharm class
thiazide, potassium wasting diuretic
hydrochlorothiazide MOA
reduce blood volume through excretion of water and potassium, reducing blood volume and BP
hydrochlorothiazide side effects
hypokalemia, hyponatremia, hypotension, dizzeness, dehydration
hydrochlorothiazide patient consideration
observe hypokalemia, increase potassium-containing foods, don’t give to patients who don’t make urine
hydrochlorothiazide drug interactions
hypokalemia increases risk of digoxin toxicity
furosemide therapeutic class
diuretic, antihyperintensive
furosemide pharm calss
loop diuretic, potent potassium wasting diuretic
furosemide MOA
works in loop of Henle to promote the excretion of sodium and water and reduces blood volume, causes potassium wasting, produces rapid diuresis when given IV
furosemide side effects
hypokalemia (check potassium before giving), orthostatic HTN, ototoxicity and nephrotoxicity, hyperglycemia
furosemide nursing considerations
monitor intake and output, k+ levels, blood glucose, hearing loss, use cautiously with drugs that deplete K+
spironolactone therapeutic class
antihypertensives, reduces edema
spironolactone pharm class
potassium-sparing diuretic, aldosterone antagonist
spironolactone MOA
inhibits aldosterone which increases water and sodium excretion (RAAS), commonly used to treat HTN along with other anti-HTN drugs, slows progression of heart failure
spironolactone side effects
hyperkalemia (especially if taken with ACE inhibitors), gynecomastia
spironolactone nursing considerations
give with food to increase absorption of drugs, do NOT give K+ supplements or salt-substitute, warm male patients about gynecomastia
lisinopril therapeutic class
drug for HTN and heart failure
lisinopril pharm class
ACE inhibitor
lisinopril MOA
inhibits ACE which is responsible for converting angiotensin I to angiotensin II which ultimately blocks effects of aldosterone
lisinopril side effects
cough and swelling and tongue fullness is expected, angioedema, hyperkalemia, hypotension, used with thiazide diuretics
losartan therapeutic class
hypertension
losartan pharm class
angiotensin II receptor blocker
losartan MOA
vasodialation and reduced blood volume
losartan side effects
HYPOglycemia, dizziness, stuffy nose, fatigue
losartan Black box warning
do not use when pregnant
losartan nursing considerations
increase risk for hyperkalemia
metoprolol therapeutic class
HTN and heart failure
metoprolol pharm class
beta-adrenergic blocker (selective for beta 1)
metoprolol MOA
reduces sympathetic stimulation of heart and decreases cardiac workload, preferred for patients with respiratory disease
metoprolol side effects
hypotension, bradycardia, enhance hypoglycemic affects of insulin
metoprolol black box warning
withdrawl may make angina worse or casue MI
metoprolol contraindication
heart block, cardiogenic shock, hypotension, overt cardiac failure
nifedipine therapeutic class
HTN drug
nifedipine pharm class
calcium channel blocker
nifedipine MOA
blocks calcium channels in smooth muscle of coronary arteries and less oxygen consumed by heart and fall in BP
nifedipine side effects
dizziness, hypotension, headache, gerd
nifedipine nursing considerations
give cautiously with other antihypertensives, digoxin toxicity, don’t take with grapefruit juice, don’t drink alcohol