HTN Prototypes Flashcards
hydrochlorothiazide therapeutic class:
diuretic
hydrochlorothiazide pharm class
thiazide, potassium wasting diuretic
hydrochlorothiazide MOA
reduce blood volume through excretion of water and potassium, reducing blood volume and BP
hydrochlorothiazide side effects
hypokalemia, hyponatremia, hypotension, dizzeness, dehydration
hydrochlorothiazide patient consideration
observe hypokalemia, increase potassium-containing foods, don’t give to patients who don’t make urine
hydrochlorothiazide drug interactions
hypokalemia increases risk of digoxin toxicity
furosemide therapeutic class
diuretic, antihyperintensive
furosemide pharm calss
loop diuretic, potent potassium wasting diuretic
furosemide MOA
works in loop of Henle to promote the excretion of sodium and water and reduces blood volume, causes potassium wasting, produces rapid diuresis when given IV
furosemide side effects
hypokalemia (check potassium before giving), orthostatic HTN, ototoxicity and nephrotoxicity, hyperglycemia
furosemide nursing considerations
monitor intake and output, k+ levels, blood glucose, hearing loss, use cautiously with drugs that deplete K+
spironolactone therapeutic class
antihypertensives, reduces edema
spironolactone pharm class
potassium-sparing diuretic, aldosterone antagonist
spironolactone MOA
inhibits aldosterone which increases water and sodium excretion (RAAS), commonly used to treat HTN along with other anti-HTN drugs, slows progression of heart failure
spironolactone side effects
hyperkalemia (especially if taken with ACE inhibitors), gynecomastia
spironolactone nursing considerations
give with food to increase absorption of drugs, do NOT give K+ supplements or salt-substitute, warm male patients about gynecomastia
lisinopril therapeutic class
drug for HTN and heart failure
lisinopril pharm class
ACE inhibitor
lisinopril MOA
inhibits ACE which is responsible for converting angiotensin I to angiotensin II which ultimately blocks effects of aldosterone
lisinopril side effects
cough and swelling and tongue fullness is expected, angioedema, hyperkalemia, hypotension, used with thiazide diuretics
losartan therapeutic class
hypertension
losartan pharm class
angiotensin II receptor blocker
losartan MOA
vasodialation and reduced blood volume
losartan side effects
HYPOglycemia, dizziness, stuffy nose, fatigue