GI Prototypes Flashcards
omprezole TC
anti ulcer drug
omprezole PC
proton pump inhibitor
omprezole MOA
Reduce acid secretion by binding to H+K+-ATPase (the “pump” that releases acid onto the GI mucosa), worls better than H2 blockers, short term therepy for peptic ulcers
omprezole admin
Give 30 minutes before meal, long term can casue osteoporosis
omeprazole adverse effects
can cause rare blood disorders so use for as short a time as possible. May cause B12 deficiency.
aluminum hydroxide TC
anti heartburn
aluminum hydroxide PC
antacid
aluminum hydroxide MOA
used with other antacids and can combine with magnesium to increase effectivemenss
aluminum hydroxide admin
at least 2 hrs before or 1 hr after other drugs
aluminum hydroxide SEs
constipation
psyllium TC
bulk forming laxative
psyllium PC
herbal agent
psyllium MOA
made from the seeds of platain plant, take with water
psyllium Admin
take with 8ox water!!!! AND give immediately, can swell in esophagus if not enough water
psyllium contraindications
dont give with undiagnosed abdominal pain, fecal impaction or obstruction
diphenoxlate w atropine TC
antidiarrheal
diphenoxlate w atropine PC
opioid
diphenoxlate w atropine PC
slows peristalsis and allows water absorption, acts in 45 to 60 mins, atropine prevents from taking too much
diphenoxlate w atropine adverse effects
anticholinergic, dry mouth, drowsiness, tachycardia
sulfasalazine TC
drug for inflammatory bowel disease
sulfasalazine PC
5-aminosalicylate
sulfasalazine MOA
anti-inflammatory that treats symptoms of ulcerative colitis, used to treat rheumatoid arthritis
sulfasalazine admin
dont use with sulfa allergy
sulfasalazine adverse effects
nausea, vomiting, anorexia, headache, can cause stevens-johnsons syndrome
sulfasalazine contraindications
those with sulfa or asprin allergy, hepatic impairment, anemia, or blood disorders