Endocrine and Diabetes Drugs

Question 1

demopressin TC

Answer 1

drug for DI

Question 2

demopressin PC

Answer 2

ADH (anti-diuretic hormone)

Question 3

demopressin MOA

Answer 3

acts on kidneys to reabsorb water, controls acute symptoms of DI

Question 4

demopressin admin

Answer 4

PO, intranasal, or parentaral, check Na, monitor I/Os

Question 5

demopressin adverse effects

Answer 5

water intoxication- drowsiness, headache, listlessness, coma

Question 6

demopressin BBW

Answer 6

can cause hyponatremia

Question 7

demopressin contraindications

Answer 7

don’s use in DI caused by kidney disease, heart failure patients,

Question 8

levothyroxine TC

Answer 8

thyroid hormone

Question 9

levothyroxine PC

Answer 9

TH replacement

Question 10

levothyroxine MOA

Answer 10

synthetic t4, serum TSH is checked to see if replacement is working, TSH will decrease as thyroxine inproves

Question 11

levothyroxine adverse effects

Answer 11

rare, but can cause hyperthyroidism: palpitations, anxiety, insomnia, heat intolerance, weight loss

Question 12

levothyroxine contraindications

Answer 12

CV conditions or MI, use cautiously in older adults, can cause adrenal crisis

Question 13

hydrocortisone TC

Answer 13

adrenal hormone

Question 14

hydrocortisone PC

Answer 14

corticosteroid

Question 15

hydrocortisone MOA

Answer 15

identical to cortisol, when used for inflammation it’s given at high doses

Question 16

hydrocortisone adverse effects

Answer 16

rare at replacement therapy doses, Cushings can result form lomng term high doses

Question 17

hydrocortisone contraindications

Answer 17

drug hypersensitivity, known infections, diabetes, osteoporosis, psychoses, liver disease, hypothyroidism, decrease response to vaccines

Question 18

Insulin TC

Answer 18

parenteral drug for diabetes, replacement pancreatic hormone

Question 19

Insulin PC

Answer 19

hypoglycemic drug

Question 20

Insulin MOA

Answer 20

cellular uptake of glucose,

Question 21

Insulin admin

Answer 21

ensure patient has had sufficient food, check blood sugar

Question 22

Insulin adverse effects

Answer 22

hypoglycemia, lipohypertrophy at injection sites

Question 23

Insulin contraindications

Answer 23

hypokalemia

Question 24

Insulin lab tests

Answer 24

blood glucose, hemoglobin a1c

Question 25

glucagon TC

Answer 25

increases blood glucose, hypoglycemia antidote,

Question 26

glucagon PC

Answer 26

glycogenolytic hormone

Question 27

glucagon moa

Answer 27

used for hypoglycemia reations, IM, stimulates glycogenolysis to increase blood glucose

Question 28

glucagon adverse effects

Answer 28

nausea, vomitting, low blood pressure

Question 29

insulin aspart “Novalog”

Answer 29

RAPID, given just before meal, onset 10-20 min, peak 1-3 hrs, duration 3-5 hr

Question 30

insulin regular

Answer 30

SHORT, given 30-60 min before meal, onset 30-60 mins, peak 2-4 hr, duration 5-8hr

Question 31

insulin isophane “NPH”

Answer 31

INTERMEDIATE, given 30 mins before first meal of day, onset 1-2 hr, peak 4-12 hr, duration 18-24hr

Question 32

insulin glargine “Lantus”

Answer 32

LONG, onset 1.5hr, peak none, duration 24hrs

Question 33

metformin ther class

Answer 33

anti diabetic drug

Question 34

metformin pharm class

Answer 34

biguanide

Question 35

metformin MOA

Answer 35

reduces fasting and post meal glucose levels by decreasing hepatic production of glucose (gluconeogensis) and reduces insulin resistance; lowers triglycerides and LDLs, promotes anorexia

Question 36

metformin adverse effects

Answer 36

GI related: nausea, vomiting, abdominal discomfort, dairrhea; metabolic taste and anorexia

Question 37

metformin BBW

Answer 37

lactic acidosis is rare but potentially fatal, increased in patients w CKD, liver disease, infection, alcohol intake, shock or hypoxemia

Question 38

metformin contraindications

Answer 38

patients in BBW, do not take for 2 days prior and after IV radiographic contrast