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Pharm 1 > Hematologic Drugs > Flashcards

Hematologic Drugs Flashcards

1
Q

cyanocobalmin (B12) therapeutic class:

A

drug for anemia

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2
Q

cyanocobalmin (B12) pharm class:

A

vitamin supplement

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3
Q

cyanocobalmin (B12) MOA:

A

for people with B12 deficiency anemia, given IM

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4
Q

cyanocobalmin (B12) adverse effects:

A

uncommon but anaphylaxis is possible
(link between depression and lack of b12)

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5
Q

ferrous sulfate (iron) therapeutic class:

A

anti-anemic drug

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6
Q

ferrous sulfate (iron) pharm class:

A

iron supplement

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7
Q

ferrous sulfate (iron) MOA:

A

provides iron needed to make hemoglobin

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8
Q

ferrous sulfate (iron) adverse effects

A

GI effects, constipation, take only until anemia corrected, excess may be toxic

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9
Q

ferrous sulfate (iron) drug interactions

A

take alone, can be very toxic

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10
Q

epoiten alpha therapeutic class:

A

erythropoiesis stimulating drug

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11
Q

epoiten alpha pharm class

A

erythropoietin

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12
Q

epoiten alpha MOA:

A

stimulates production of RBCs

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13
Q

epoiten alpha admin alerts

A

given subcu

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14
Q

epoiten alpha adverse effects

A

HTN, headache, fever, nacho

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15
Q

epoiten alpha BBW

A

increased risk of CV and thrombolic events (MI, stroke, DVT)

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16
Q

filgrastim therapeutic class:

A

drug for increasing neutrophil production

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17
Q

filgrastim pharm class:

A

colony stimulating factor

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18
Q

filgrastim MOA

A

stimulate bone marrow to make and release neutrophils, shortens length of neutropenia, oftne given to pateints after chemo

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19
Q

filgrastim administration

A

usually given subq

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20
Q

filgrastim adverse effects:

A

bone pain, can cause anaphylaxis, excessive WBC production

21
Q

heparin therepeutic class

A

anticoagulant

22
Q

heparin pharm class

A

indirect thrombin inhibitor

23
Q

heparin MOA

A

short acting and given IV to rapidly prevent further clot formation, and it an indirect thrombin inhibitor

24
Q

heparin nursing consideration

A

effect is measured aPTT

25
enoxaparin therapeutic class
anticoagulant
26
enoxaparin pharm class
low molecular weight heparin
27
enoxaparin MOA
LMWH is long-acting, given SQ and the onset of action is about 1 hr
28
enoxaparin nursing consoderations
watch for platelet counts, and given every 12 hrs
29
antidote for enoxiparin or heparin
protamine sulfate
30
Heparin BBW
epidural or spinal hematomas may occur while on heparin in patients receiving spinal anesthesia or lumbar puncture
31
warfarin therapeutic class
anticoagulant (oral)
32
warfarin pharm class
vitamin K antagonist
33
warfarin actions
prevention of stroke, DVT and pulmonary embolism, given to high risk patients following an MI or Afib
34
warfarin BBW
can cause fatal bleeding
35
warfarin contraindications
patients with recent trauma, internal bleeding, bleeding disorder, intracranial hemorrhage, severe HTBN, or liver/kidney disease
36
warfarin antidote
vitamin K
37
how to monitor warfarin
PT/ INR, which is activated partial thromboplastin time (how long does it take your blood to clot), normal seconds, should be 1.5-2.5 normal value on heparin
38
clopidogrel (Plavix) therapeutic class
antiplatelet drug
39
clopidogrel (Plavix) pharm class
adenosine phosphate (ADP) receptor blocker (ADP promotes platelet aggregation)
40
clopidogrel (Plavix) actions
reduce the rate of MI or stroke w/ acute STEMI given to prevent thrombi in coronary stents; very expensive, given to those who can"t take aspirin
41
clopidogrel (Plavix) administration
do not crush
42
clopidogrel (Plavix) adverse effects
bruising, rash, flu like symptoms
43
clopidogrel (Plavix) BBW
some cannot metabolize
44
clopidogrel (Plavix) contraindications
do not give to anyone with active bleeding
45
alteplase therapeutic class
dissolves clots
46
alteplase pharm class
thromolytic
47
alteplase actions
converts plasminogen to plasmin whihc dissolves fibrin clots, used for stroe due to thrombus
48
alteplase admin
must be given within 12 hrs of symptoms of MI and within 3 hrs of stroke
49
alteplase adverse effects
bleeding, can cause anaphylaxis, don't use with other anticoagulants

Pharm 1 (13 decks)

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