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Pharm 1 > Hematologic Drugs > Flashcards

Hematologic Drugs Flashcards

1
Q

cyanocobalmin (B12) therapeutic class:

A

drug for anemia

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2
Q

cyanocobalmin (B12) pharm class:

A

vitamin supplement

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3
Q

cyanocobalmin (B12) MOA:

A

for people with B12 deficiency anemia, given IM

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4
Q

cyanocobalmin (B12) adverse effects:

A

uncommon but anaphylaxis is possible
(link between depression and lack of b12)

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5
Q

ferrous sulfate (iron) therapeutic class:

A

anti-anemic drug

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6
Q

ferrous sulfate (iron) pharm class:

A

iron supplement

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7
Q

ferrous sulfate (iron) MOA:

A

provides iron needed to make hemoglobin

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8
Q

ferrous sulfate (iron) adverse effects

A

GI effects, constipation, take only until anemia corrected, excess may be toxic

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9
Q

ferrous sulfate (iron) drug interactions

A

take alone, can be very toxic

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10
Q

epoiten alpha therapeutic class:

A

erythropoiesis stimulating drug

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11
Q

epoiten alpha pharm class

A

erythropoietin

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12
Q

epoiten alpha MOA:

A

stimulates production of RBCs

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13
Q

epoiten alpha admin alerts

A

given subcu

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14
Q

epoiten alpha adverse effects

A

HTN, headache, fever, nacho

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15
Q

epoiten alpha BBW

A

increased risk of CV and thrombolic events (MI, stroke, DVT)

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16
Q

filgrastim therapeutic class:

A

drug for increasing neutrophil production

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17
Q

filgrastim pharm class:

A

colony stimulating factor

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18
Q

filgrastim MOA

A

stimulate bone marrow to make and release neutrophils, shortens length of neutropenia, oftne given to pateints after chemo

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19
Q

filgrastim administration

A

usually given subq

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20
Q

filgrastim adverse effects:

A

bone pain, can cause anaphylaxis, excessive WBC production

21
Q

heparin therepeutic class

A

anticoagulant

22
Q

heparin pharm class

A

indirect thrombin inhibitor

23
Q

heparin MOA

A

short acting and given IV to rapidly prevent further clot formation, and it an indirect thrombin inhibitor

24
Q

heparin nursing consideration

A

effect is measured aPTT

25
Q

enoxaparin therapeutic class

A

anticoagulant

26
Q

enoxaparin pharm class

A

low molecular weight heparin

27
Q

enoxaparin MOA

A

LMWH is long-acting, given SQ and the onset of action is about 1 hr

28
Q

enoxaparin nursing consoderations

A

watch for platelet counts, and given every 12 hrs

29
Q

antidote for enoxiparin or heparin

A

protamine sulfate

30
Q

Heparin BBW

A

epidural or spinal hematomas may occur while on heparin in patients receiving spinal anesthesia or lumbar puncture

31
Q

warfarin therapeutic class

A

anticoagulant (oral)

32
Q

warfarin pharm class

A

vitamin K antagonist

33
Q

warfarin actions

A

prevention of stroke, DVT and pulmonary embolism, given to high risk patients following an MI or Afib

34
Q

warfarin BBW

A

can cause fatal bleeding

35
Q

warfarin contraindications

A

patients with recent trauma, internal bleeding, bleeding disorder, intracranial hemorrhage, severe HTBN, or liver/kidney disease

36
Q

warfarin antidote

A

vitamin K

37
Q

how to monitor warfarin

A

PT/ INR, which is activated partial thromboplastin time (how long does it take your blood to clot), normal seconds, should be 1.5-2.5 normal value on heparin

38
Q

clopidogrel (Plavix) therapeutic class

A

antiplatelet drug

39
Q

clopidogrel (Plavix) pharm class

A

adenosine phosphate (ADP) receptor blocker (ADP promotes platelet aggregation)

40
Q

clopidogrel (Plavix) actions

A

reduce the rate of MI or stroke w/ acute STEMI given to prevent thrombi in coronary stents; very expensive, given to those who can”t take aspirin

41
Q

clopidogrel (Plavix) administration

A

do not crush

42
Q

clopidogrel (Plavix) adverse effects

A

bruising, rash, flu like symptoms

43
Q

clopidogrel (Plavix) BBW

A

some cannot metabolize

44
Q

clopidogrel (Plavix) contraindications

A

do not give to anyone with active bleeding

45
Q

alteplase therapeutic class

A

dissolves clots

46
Q

alteplase pharm class

A

thromolytic

47
Q

alteplase actions

A

converts plasminogen to plasmin whihc dissolves fibrin clots, used for stroe due to thrombus

48
Q

alteplase admin

A

must be given within 12 hrs of symptoms of MI and within 3 hrs of stroke

49
Q

alteplase adverse effects

A

bleeding, can cause anaphylaxis, don’t use with other anticoagulants

Pharm 1 (13 decks)

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