Homeostasis Flashcards
Define homeostasis
Process of maintaining a stable internal environment or being in a balanced state even with external changes to allow body to function properly
List the general steps of the pathways of homeostasis
- Stimulus produces change
- Change detected by receptor
- Input into control center
- Output into effector
- Response of effector feeds back to magnitude of stimulus
- Returns change to homeostasis
What are the 2 types of nerves?
Sensory and motor
The autonomic nervous system is _____________ (somatic or visceral) efferent
Visceral
The ANS is divided into:
SNS and PNS
Describe how the layout of the ANS work in homeostasis
Visceral receptors receive signal and take it afferently into ANS integration centers
Sympathetic and parasympathetic efferent relay the information into autonomic effectors (cardiac/smooth mm) to initiate response
Which outflow is in the PSNS?
Craniosacral outflow
What type of energy action is PSNS associated with?
Anabolism / conservation
SNS is associated with ___________ outflow, thus energy ___________
Thoracolumbar; catabolism
Which neurotransmitter is used by the SNS in pre-synaptic aspect?
ACh
Which neurotransmitter is used by the SNS in pre-synaptic aspect?
ACh
What neurotransmitter is associated with post ganglionic SNS?
Epi/norepinephrine
Describe PSNS release of neurotransmitters
Both (pre and post) axons release ACh
Epinephrine and norepinephrine are what type of neurotransmitter?
Catecholamine
In SNS, which axons are longer?
Post synaptic/ganglionic
Describe PSNS axon length
Pre is longer than post
Sympathetic is fight/flight or rest and digest
Fight/flight
Does sympathetic or parasympathetic increase blood flow to GIT?
Parasympathetic
Which 2 nerves are associated with Craniosacral outflow?
Vagus and pelvic
Thoracolumbar associates with which nerves?
Vertebral, hypogastric
Ionotropic receptors are ___________
Cholinergic - nicotinic on skeletal muscle
Metabotropic is associated with _________
Muscarinic
Which synthesized things are associated with cholinergic receptors?
Choline, choline acetyltransferase
Degradation at cholinergenic receptors is done by:
Acetylcholinesterase (AChE)
Muscarinic recepors are signaling the ___________ and __________
Stomach and lungs
What type of receptors are at the NMJ?
Nicotinic
Monoamines/catecholamines are degraded by which 2 Substances?
Monoamine oxidase. (MAO) and Catechol-o-methyl transferase (COMT)
Which receptors are used in monoamine signaling?
Alpha and beta adrenergic receptors
What is synthesized with monoamines/catecholamines?
Tyrosine, tyrosine hydroxylase, dopa decarboxylase
In the CNS autonomic flow, the __________ is associated with behavioral arousal, emotion, stress response and homeostasis
Brain
What integrates the automatic function with arousal and pain stimulation in CNS Autonomic outflow?
Tegmentum
Tonic control of blood pressure and respiratory rhythms is done by?
Medulla
List some stuff that the spinal cord is in charge of
- micturition
- defecation
- erection
What is the name of the system in mammals in the Triune brain theory?
Limbic System
What is the limbic system involved in the mammal brain?
Decisions - emotions, memory, habits
What part of the brain is connected to the structures within the limbic system and brainstem?
Hypothalamus
Describe how the Hypothalamus and limbic system work together
Together they control the endocrine system and autonomic nervous system to maintain homeostasis
List some functions of the Hypothalamus
- maintain body temp
- control repro functions
- control food intake
What are the 3 types homeostatic responses coordinated by the hypothalamus?
Behavioral, endocrine, autonomic
List a function paraventricular and supraoptic nuclei
Produce ADH and oxytocin
Thermal regulation is done by which hypothalamic nuclei
Anterior nucleus
What hypothalamic nuclei contains sexually dimorphic nucleus?
Preoptic area
The suprachiasmatic nucleus in the HT receives input from the _______________
Retina
Stimulation of which HT nuclei results in obesity and savage behavior?
Dorsomedial nucleus
Posterior nucleus is involved in stimulating which NS?
Sympathetic
Which HT nuclei if stimulated induces eating?
Lateral nucleus
Which HT nuclei is the statiety center?
Ventromedial nucleus
Arcuate nucleus produces what?
Produces hypothalamic releasing factors
What are the 2 secreting endocrine glands in the hypothalamus?
Anterior and posterior pituitary
Which pituitary secretes Oxytocin and ADH?
Posterior pituitary
List some hormones are secreted by the anterior pituitary?
FSH, LH, PRL, endorphins
Where do the HT secrete the regulatory hormones?
Into local circulation that drains into anterior pituitary
How does the HT control the endocrine system?
By secreting oxytocin and vasopressin into general circulation
Describe how the HT compares input to biological set points
Receives contextual information and sensory inputs
Compare heat control in the hypothalamus area
Preoptic area - heat dissipation
Posterior area - heat conservation
What type of pathways in the CNS control food intake and energy expenditure by influencing behavior, autonomic activity and metabolic rate
Anabolic and catabolic
Energy balance and fat storage mechanisms control the amounts of _____________and ______________
Leptin and insulin
Define leptin
Satiety hormone
Name the hunger hormone
Ghrelin
If the ventromedial hypothalamus was destroyed, what can be a consequence?
Obesity
Stimulation of which HT nuclei causes weight loss?
Lateral HT
Which HT nuclei is the satiety center ?
Ventromedial
True or false: the hypothalamus can mediate immune responses
True
Which HT nuclei is responsible for controlling circadian rhythms?
Suprachiasmatic nucleus
Which is the sleep promoting nucleus?
Ventrolateral Preoptic nucleus