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MY NUR 326 > HIV Pharm > Flashcards

HIV Pharm Flashcards

1
Q

what drug is in Nucleoside reverse transcriptase inhibitors (NRTIs)

A

zidovudine

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2
Q

what drug is in Non-nucleoside reverse transcriptase inhibitors (NNRTIs)

A

efavirenz

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3
Q

MOA of zidovudine

A

inhibit reverse transcriptase

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4
Q

indication of zidovudine

A

delay or reverse loss of immune function
decrease aids related complications
prolong life

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5
Q

adverse effects of zidovudine

A

severe anemia and neutropenia
lactic acidosis in female or obese people

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6
Q

nursing considerations of zidovudine

A

when used in combination it decreases viral load, delays onset of AIDs, reduce symptom severity

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7
Q

MOA of efavirenz

A

inhibit reverse transcriptase

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8
Q

indication of efavirenz

A

Delay or reverse loss of immune function
Decrease AIDs related complications
Prolong life

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9
Q

adverse effects of efavirenz

A

rash, CNS symptoms

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10
Q

what drug is a integrase inhibitor

A

raltegravir

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11
Q

MOA of raltegravir

A

inhibits integrase

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12
Q

protease inhibitor drug

A

lopinavir/ritonavir

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13
Q

lopinavir/ritonavir MOA

A

inhibits protease

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14
Q

adverse effects of lopinavir/ritonavir

A

hyperglycemia, lipodystrophy, hyperlipidemia, bone loss

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15
Q

nursing considerations of Lopinavir/ritonavir

A

do not use with -statins

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16
Q

fusion inhibitor drug

A

enfuvirtide

17
Q

MOA of enfuvirtide

A

blocks entry of HIV into CD4 T cells

18
Q

adverse effects of enfuvirtide

A

injection site reactions, pneumonia, hypersensitivity

19
Q

CCR5 antagonist drug

A

maraviroc

20
Q

MOA of maraviroc

A

blocks entry into CD4 cells

21
Q

black box warning of maraviroc

A

liver injury

MY NUR 326 (12 decks)

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