HIV Pharm

Question 1

what drug is in Nucleoside reverse transcriptase inhibitors (NRTIs)

Answer 1

zidovudine

Question 2

what drug is in Non-nucleoside reverse transcriptase inhibitors (NNRTIs)

Answer 2

efavirenz

Question 3

MOA of zidovudine

Answer 3

inhibit reverse transcriptase

Question 4

indication of zidovudine

Answer 4

delay or reverse loss of immune function
decrease aids related complications
prolong life

Question 5

adverse effects of zidovudine

Answer 5

severe anemia and neutropenia
lactic acidosis in female or obese people

Question 6

nursing considerations of zidovudine

Answer 6

when used in combination it decreases viral load, delays onset of AIDs, reduce symptom severity

Question 7

MOA of efavirenz

Answer 7

inhibit reverse transcriptase

Question 8

indication of efavirenz

Answer 8

Delay or reverse loss of immune function
Decrease AIDs related complications
Prolong life

Question 9

adverse effects of efavirenz

Answer 9

rash, CNS symptoms

Question 10

what drug is a integrase inhibitor

Answer 10

raltegravir

Question 11

MOA of raltegravir

Answer 11

inhibits integrase

Question 12

protease inhibitor drug

Answer 12

lopinavir/ritonavir

Question 13

lopinavir/ritonavir MOA

Answer 13

inhibits protease

Question 14

adverse effects of lopinavir/ritonavir

Answer 14

hyperglycemia, lipodystrophy, hyperlipidemia, bone loss

Question 15

nursing considerations of Lopinavir/ritonavir

Answer 15

do not use with -statins

Question 16

fusion inhibitor drug

Answer 16

enfuvirtide

Question 17

MOA of enfuvirtide

Answer 17

blocks entry of HIV into CD4 T cells

Question 18

adverse effects of enfuvirtide

Answer 18

injection site reactions, pneumonia, hypersensitivity

Question 19

CCR5 antagonist drug

Answer 19

maraviroc

Question 20

MOA of maraviroc

Answer 20

blocks entry into CD4 cells

Question 21

black box warning of maraviroc

Answer 21

liver injury