Anemia Pharm Flashcards
what drug is in the erythropoiesis stimulating agent class
epoetin alfa
MOA of epoetin alfa
mimics human erythropoietin
what does erythropoietin do
stimulates RBC production in the bone marrow
who do you give epoetin alfa to
chronic kidney failure
HIV infection on drug therapy
anemia 2° chemotherapy in certain cancers
pre-operative in patients with anemia
when considering epoetin alfa, what is the hgb you will not give it to
if someone’s hgb is >10 DO NOT GIVE
Nursing considerations for epoetin alfa
weigh the risks versus benefits
- use lowest dose possible to reduce the need to transfuse
- monitor BP before and during therapy
- monitor hgb levels
In a chronic kidney patient what can epoetin alfa cause
increased mortality and serious cardiovascular events
in cancer patients what can epoetin alfa cause
increased mortality and turmor progression
in surgery patients what can epoetin cause
increased thromboembolic events and mortality
what drug is in the iron therapy class
ferrous sulfate
indications for ferrous sulfate
iron deficiency/prevention
moa of ferrous sulfate
taken up by bone marrow cells to make hemoglobin
adverse effects of ferrous sulfate
GI disturbances
teeth staining
tarry stools
Nursing considerations for iron therapy
antacids reduce absorption
food helps prevent GI side effects
food decreases absorption by 50-70%
what drug is a parenteral iron
iron dextran